ArticleScientific reports2025
A pilot study on the prevalence and patterns of haemoglobinopathies in Datia District, Madhya Pradesh, India.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Haemoglobinopathies are the most common inherited disorder of Red Blood Cells across the globe and one of the major public health problems in many regions of India. Variation in ethnic and regional prevalence is observed in many parts of India. The prevalence and pattern of haemoglobinopathies in Datia region has not been reported limiting the knowledge of disease profiles in this region. The present work aimed to find the broad view of various haemoglobinopathies in the local area and population at risk. To identify prevalence and patterns of three blood disorders namely sickle cell anaemia, β-thalassemia major and G-6-P-D deficiency samples were collected from the patients attending various OPDs of District Hospital, Datia, Madhya Pradesh, India. All anaemic patients referred by Government District Hospital, Datia District, M.P. were screened for various haemoglobinopathies. A total of 605 cases were received from September 2017 to March 2020 at the Model Rural Health Research Unit (MRHRU), Datia, M.P. All 605 samples were tested for different haemoglobinopathies by solubility test and G6PD deficiency, cellulose acetate electrophoresis, and suspected cases were confirmed from HPLC. A total of 605 patients were screened for haemoglobinopathies from District Hospital, Datia. It was found that 13 cases (2.14%) were of β thalassemia trait and other rare variants followed by 4 cases (0.66%) of sickle cell trait. A total of 3 cases (0.5%) of β thalassemia major were observed in a total sample of 605. No previous studies have reported the status of haemoglobinopathies in this region, since this region is known for tribes it is essential to have study of blood genetic disorders. Novelty of this study is that it is the first report from this region to the best of our knowledge. Very low prevalence rate of sickle cell anaemia and thalassemia was observed. So, large-scale screening in the region is required for identifying the true burden. Chelation therapy, gene therapies in future could be great help to the patients of this region.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.