Evidence map›Paper›PMID 41326325›Full record

ArticleVox sanguinis2026

International Society of Blood Transfusion Working Party on Red Cell Immunogenetics and Blood Group Terminology Report of Gothenburg, Barcelona and four virtual business meetings: Update on blood group systems.

Catherine A Hyland, Lilian Castilho, Qing Chen, Frederik Banch Clausen, Gregory A Denomme, Yann Fichou, Willy Albert Flegel, Aline Floch, Nicholas S Gleadall, Åsa Hellberg and 25 more

Abstract read
In one paragraph

Article in Vox sanguinis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Catherine A HylandAustralian Red Cross Lifeblood, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0002-4124-6168
Lilian CastilhoUniversity of Campinas/Hemocentro, Campinas, Brazil.
Qing ChenDepartment of Transfusion Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, China.
Frederik Banch ClausenDepartment of Clinical Immunology, Laboratory of Blood Genetics, Copenhagen University Hospital, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-2487-5373
Gregory A DenommeGrifols Diagnostic Solutions, Emeryville, California, USA.ORCID https://orcid.org/0000-0001-8727-1679
Yann FichouUniversity of Brest, Inserm, EFS, UMR1078, GGB, Brest, France.ORCID https://orcid.org/0000-0002-5104-9125
Willy Albert FlegelDepartment of Transfusion Medicine, NIH Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0002-1631-7198
Aline FlochLaboratoire de biologie médicale de référence en immunohématologie moléculaire, Etablissement français du sang Ile de France, Créteil, France.ORCID https://orcid.org/0000-0003-3238-4566
Nicholas S GleadallVictor Dahdaleh Heart and Lung Research Institute, Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
Åsa HellbergDepartment of Clinical Immunology and Transfusion Medicine, Skåne University Hospital, Lund, Sweden.ORCID https://orcid.org/0000-0002-7000-1899
Yanli JiInstitute of Blood Transfusion and Hematology, Guangzhou Blood Center, Guangzhou Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0001-6792-5612
Vanja Karamatic CrewInternational Blood Group Reference Laboratory, NHS Blood and Transplant, Bristol, UK.
Margaret A KellerAmerican Red Cross Biomedical Services, Philadelphia, Pennsylvania, USA.
William J LaneDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-1097-5229
Peter C LigthartDepartment of Diagnostic Immunohematology, Sanquin, Amsterdam, The Netherlands.
Christine Lomas-FrancisImmunohematology and Genomics Laboratory, New York Blood Center Enterprises (NYBCe), Long Island City, New York, USA.
Genghis H LopezAustralian Red Cross Lifeblood, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0001-8568-0604
Celina MontemayorCanadian Blood Services, Brampton, Ontario, Canada.
Núria NoguésImmunohematology Reference Laboratory, Banc de Sang i Teixits, Barcelona, Spain.
Gorka OchoaImmunohematology and Genomics Laboratory, New York Blood Center Enterprises (NYBCe), Long Island City, New York, USA.
Martin L OlssonDepartment of Clinical Immunology and Transfusion Medicine, Skåne University Hospital, Lund, Sweden.ORCID https://orcid.org/0000-0003-1647-9610
Thierry PeyrardEtablissement Français du Sang, La Plaine Saint-Denis, France.
Kshitij SrivastavaDepartment of Transfusion Medicine, NIH Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Jill R StorryDepartment of Clinical Immunology and Transfusion Medicine, Skåne University Hospital, Lund, Sweden.ORCID https://orcid.org/0000-0003-2940-2604
Yoshihiko TaniCentral Blood Institute, Blood Service Headquarters, Japanese Red Cross, Tokyo, Japan.
Nicole ThorntonInternational Blood Group Reference Laboratory, NHS Blood and Transplant, Bristol, UK.
Ellen van der SchootDepartment of Experimental Immunohematology, Sanquin, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-8065-3540
Sunitha VegeImmunohematology and Genomics Laboratory, New York Blood Center Enterprises (NYBCe), Long Island City, New York, USA.
Barbera VeldhuisenDepartment of Diagnostic Immunohematology, Sanquin, Amsterdam, The Netherlands.
Franz F WagnerGerman Red Cross Blood Service NSTOB, Springe, Germany.
Christof WeinstockGerman Red Cross Blood Service Baden-Württemberg - Hessen, Ulm, Germany.
Silvano WendelBlood Bank, Hospital Sirio-Libanes, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-1941-7733
Connie M WesthoffImmunohematology and Genomics Laboratory, New York Blood Center Enterprises (NYBCe), Long Island City, New York, USA.
Vered YahalomRabin Medical Center, Petach Tiqva and Faculty of Medical and Health Science, Tel Aviv University, Tel Aviv, Israel.
Christoph GassnerInstitute of Translational Medicine, Private University in the Principality of Liechtenstein, Triesen, Liechtenstein.

Funding

Laboratory Services Section, Department of Transfusion Medicine Core ReportZICCL002128 · CLC · CLINICAL CENTER · PI FLEGEL, WILLY · 2020 to 2025
$0k
European Union 101021487 DE-CCP-NorthFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Hans Groeber StiftungIncubation Research Program for Introducing Talents of Nanjing Drum Tower Hospital RC2022-028Intramural NIH HHS ZIC CL002128Knut and Alice Wallenberg Foundation 2020.0234Medical Science and Technology Development Foundation ZKX24022Swedish Government and County Councils ALFSKANE-446521/2022-0287Swedish Research Council 2019-01683/2024-03772Tarom Foundation
6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe International Society of Blood Transfusion (ISBT) Working Party (WP) on Red Cell Immunogenetics and Blood Group Terminology (RCI&BGT) held six business meetings between December 2021 and June 2024. This report describes the new blood group systems and antigens ratified during these meetings. MATERIALS AND

methodsCandidate systems and antigens were reviewed according to serological, genetic and biological evidence. This evidence was matched against defined criteria, and the acknowledged systems/antigens were assigned a unique identifier.

resultsFour new systems, ER (ISBT 044), CD36 (ISBT 045), ATP11C (ISBT 046) and MAL (ISBT 047), were ratified. CD36 and ATP11C were de novo entries, while ER and MAL systems resolved the genetic basis for the Er and AnWj antigens. Thirteen antigens were added to existing systems: one each to LU (005), YT (011), SC (013), LW (016), KN (022), GLOB (028); an antithetical pair to KEL (006); two antigens to RHAG (030); and three to CTL2 (039). Two CTL2 antigens defined the hitherto unresolved antithetical antigens, Cs

conclusionAs of June 2024, the ISBT has acknowledged 47 blood group systems, comprising 366 antigens. The WP continues to ratify new systems and antigens, which are available on the ISBT website (http://www.isbtweb.org/working-parties/red-cell-immunogenetics-and-blood-group-terminology/).

Indexed as

Blood Group AntigensBlood TransfusionErythrocytesImmunogeneticsTerminology as TopicBlood Grouping and CrossmatchingHumansSpainBlood Group Antigensblood groupsgeneticsgenomicsred cell antigensterminology

Identifiers

PMID41326325
PMCPMC13274570

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.