Evidence map›Paper›PMID 41326267›Full record

ArticleContemporary clinical trials2025

Acceptance and commitment therapy for people with HIV who drink at unhealthy levels: Protocol for the ACCEPT randomized controlled trial.

Sarah E Woolf-King, Emily Presutti, Olivia McKenna, Judith A Hahn, Beau Abar, Jennifer Dahne, Brooks B Gump, Kestutis G Bendinskas, Stephen A Maisto

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06648629 (Acceptance and Commitment Therapy for HIV+ Hazardous Drinkers), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06648629 narecruitingnot on this map

Acceptance and Commitment Therapy for HIV+ Hazardous Drinkers: A Randomized Clinical Trial

TypeinterventionalSponsorSyracuse UniversityRan2025 to 2028Enrolled300ConditionsHIV-1-infection, Alcohol DrinkingArmsAcceptance and Commitment Therapy (ACT), Brief Alcohol Intervention
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sarah E Woolf-KingDepartment of Psychology, Syracuse University, Syracuse, NY, USA. Electronic address: sewoolf@syr.edu.
Emily PresuttiDepartment of Psychology, Syracuse University, Syracuse, NY, USA.
Olivia McKennaDepartment of Psychology, Syracuse University, Syracuse, NY, USA.
Judith A HahnDepartment of Medicine, University of California, San Francisco, CA, USA.
Beau AbarEmergency Medicine, University of Rochester Medical Center, Rochester, NY, USA.
Jennifer DahneDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA; Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA.
Brooks B GumpDepartment of Public Health, Syracuse University, Syracuse, NY, USA.
Kestutis G BendinskasDepartment of Chemistry, State University of New York at Oswego, Oswego, NY, USA.
Stephen A MaistoDepartment of Psychology, Syracuse University, Syracuse, NY, USA.

Funding

Acceptance and Commitment Therapy for HIV+ hazardous drinkers: A randomized clinical trialR01AA030935 · NIAAA · SYRACUSE UNIVERSITY · PI SARAH E WOOLF-KING · 2023 to 2026
$2.1M
Training in Research Program on Alcohol Use by Persons with our at Risk for HIVK24AA022586 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAHN, JUDITH ALISSA · 2013 to 2023
$1.8M
NIAAA NIH HHS K24 AA022586NIAAA NIH HHS R01 AA030935
6 · The paper itself

Abstract

backgroundAlcohol consumption at unhealthy levels is associated with negative consequences at nearly every step of the HIV care continuum. We describe the rationale, aims, and study design for the ACCEPT Trial, a randomized controlled comparative efficacy trial for Acceptance and Commitment Therapy (ACT) compared to a standard brief alcohol intervention (BI) for people living with HIV (PWH) who drink at unhealthy levels.

methodsA total of 300 PWH who report drinking at unhealthy levels will be randomly assigned 1:1 to the two treatments conditions and assessed, via self-report and an alcohol biomarker, for alcohol use and comorbid symptoms of depression, anxiety, and stress at baseline, post-treatment, and 3-, 6-, and 12-months later. Symptoms of experiential avoidance, a proposed mechanism of change in the ACT condition, will also be assessed at all timepoints. We hypothesize that the two treatments will have significant, and statistically equivalent, effects on alcohol use at the post-treatment and 3-month timepoints and the ACT condition will have superior outcomes, mediated by changes to experiential avoidance, at the 6- and 12-month timepoints.

conclusionsConfirmation of the ACCEPT trial's hypotheses will provide an important tool for HIV care, treating not only unhealthy alcohol use, but also other psychiatric comorbidities seen in this population.

trial registrationClinicalTrials.gov identifier: NCT06648629.

Indexed as

Acceptance and Commitment TherapyAlcohol DrinkingAlcoholismHIV InfectionsAdultAnxietyDepressionFemaleHumansMaleRandomized Controlled Trials as TopicStress, PsychologicalAcceptance and commitment therapy (ACT)AlcoholHIVRandomized controlled trial

Identifiers

PMID41326267
PMCPMC12788168

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.