Evidence map›Paper›PMID 41326042›Full record

ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2025

Palliative care involvement and intensity of end-of-life care among adolescents and young adults with cancer: a population-based study.

Mohamed Abdelaal, Henrique Parsons, Amirrtha Srikanthan, Ahmed Al-Awamer, Pamela J Mosher, Julie Lapenskie, Sarah Cleyn, Stephen G Fung, Samantha Yoo, Shan Dhaliwal and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mohamed AbdelaalDivision of Palliative Care (Abdelaal, Parsons, Downar), Department of Medicine, University of Ottawa; Ottawa Hospital Research Institute (Abdelaal, Parsons, Lapenskie, Yoo, Dhaliwal, Downar); Division of Medical Oncology (Srikanthan), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Supportive Care (al-Awamer, Mosher), Princess Margaret Cancer Centre, University Health Network; Division of Palliative Medicine (al-Awamer), Department of Medicine, University of Toronto; Division of Child and Adolescent Psychiatry (Mosher), Hospital for Sick Children, Toronto, Ont.; Bruyère Health Research Institute (Lapenskie, Fung); The Ottawa Hospital (Cleyn); ICES uOttawa (Yoo, Dhaliwal, Tanuseputro), Ottawa, Ont.; Department of Family Medicine and Primary Care (Tanuseputro), University of Hong Kong, Hong Kong mabdelaal@toh.ca.
Henrique ParsonsDivision of Palliative Care (Abdelaal, Parsons, Downar), Department of Medicine, University of Ottawa; Ottawa Hospital Research Institute (Abdelaal, Parsons, Lapenskie, Yoo, Dhaliwal, Downar); Division of Medical Oncology (Srikanthan), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Supportive Care (al-Awamer, Mosher), Princess Margaret Cancer Centre, University Health Network; Division of Palliative Medicine (al-Awamer), Department of Medicine, University of Toronto; Division of Child and Adolescent Psychiatry (Mosher), Hospital for Sick Children, Toronto, Ont.; Bruyère Health Research Institute (Lapenskie, Fung); The Ottawa Hospital (Cleyn); ICES uOttawa (Yoo, Dhaliwal, Tanuseputro), Ottawa, Ont.; Department of Family Medicine and Primary Care (Tanuseputro), University of Hong Kong, Hong Kong.
Amirrtha SrikanthanDivision of Palliative Care (Abdelaal, Parsons, Downar), Department of Medicine, University of Ottawa; Ottawa Hospital Research Institute (Abdelaal, Parsons, Lapenskie, Yoo, Dhaliwal, Downar); Division of Medical Oncology (Srikanthan), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Supportive Care (al-Awamer, Mosher), Princess Margaret Cancer Centre, University Health Network; Division of Palliative Medicine (al-Awamer), Department of Medicine, University of Toronto; Division of Child and Adolescent Psychiatry (Mosher), Hospital for Sick Children, Toronto, Ont.; Bruyère Health Research Institute (Lapenskie, Fung); The Ottawa Hospital (Cleyn); ICES uOttawa (Yoo, Dhaliwal, Tanuseputro), Ottawa, Ont.; Department of Family Medicine and Primary Care (Tanuseputro), University of Hong Kong, Hong Kong.
Ahmed Al-AwamerDivision of Palliative Care (Abdelaal, Parsons, Downar), Department of Medicine, University of Ottawa; Ottawa Hospital Research Institute (Abdelaal, Parsons, Lapenskie, Yoo, Dhaliwal, Downar); Division of Medical Oncology (Srikanthan), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Supportive Care (al-Awamer, Mosher), Princess Margaret Cancer Centre, University Health Network; Division of Palliative Medicine (al-Awamer), Department of Medicine, University of Toronto; Division of Child and Adolescent Psychiatry (Mosher), Hospital for Sick Children, Toronto, Ont.; Bruyère Health Research Institute (Lapenskie, Fung); The Ottawa Hospital (Cleyn); ICES uOttawa (Yoo, Dhaliwal, Tanuseputro), Ottawa, Ont.; Department of Family Medicine and Primary Care (Tanuseputro), University of Hong Kong, Hong Kong.
Pamela J MosherDivision of Palliative Care (Abdelaal, Parsons, Downar), Department of Medicine, University of Ottawa; Ottawa Hospital Research Institute (Abdelaal, Parsons, Lapenskie, Yoo, Dhaliwal, Downar); Division of Medical Oncology (Srikanthan), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Supportive Care (al-Awamer, Mosher), Princess Margaret Cancer Centre, University Health Network; Division of Palliative Medicine (al-Awamer), Department of Medicine, University of Toronto; Division of Child and Adolescent Psychiatry (Mosher), Hospital for Sick Children, Toronto, Ont.; Bruyère Health Research Institute (Lapenskie, Fung); The Ottawa Hospital (Cleyn); ICES uOttawa (Yoo, Dhaliwal, Tanuseputro), Ottawa, Ont.; Department of Family Medicine and Primary Care (Tanuseputro), University of Hong Kong, Hong Kong.
Julie LapenskieDivision of Palliative Care (Abdelaal, Parsons, Downar), Department of Medicine, University of Ottawa; Ottawa Hospital Research Institute (Abdelaal, Parsons, Lapenskie, Yoo, Dhaliwal, Downar); Division of Medical Oncology (Srikanthan), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Supportive Care (al-Awamer, Mosher), Princess Margaret Cancer Centre, University Health Network; Division of Palliative Medicine (al-Awamer), Department of Medicine, University of Toronto; Division of Child and Adolescent Psychiatry (Mosher), Hospital for Sick Children, Toronto, Ont.; Bruyère Health Research Institute (Lapenskie, Fung); The Ottawa Hospital (Cleyn); ICES uOttawa (Yoo, Dhaliwal, Tanuseputro), Ottawa, Ont.; Department of Family Medicine and Primary Care (Tanuseputro), University of Hong Kong, Hong Kong.
Sarah CleynDivision of Palliative Care (Abdelaal, Parsons, Downar), Department of Medicine, University of Ottawa; Ottawa Hospital Research Institute (Abdelaal, Parsons, Lapenskie, Yoo, Dhaliwal, Downar); Division of Medical Oncology (Srikanthan), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Supportive Care (al-Awamer, Mosher), Princess Margaret Cancer Centre, University Health Network; Division of Palliative Medicine (al-Awamer), Department of Medicine, University of Toronto; Division of Child and Adolescent Psychiatry (Mosher), Hospital for Sick Children, Toronto, Ont.; Bruyère Health Research Institute (Lapenskie, Fung); The Ottawa Hospital (Cleyn); ICES uOttawa (Yoo, Dhaliwal, Tanuseputro), Ottawa, Ont.; Department of Family Medicine and Primary Care (Tanuseputro), University of Hong Kong, Hong Kong.
Stephen G FungDivision of Palliative Care (Abdelaal, Parsons, Downar), Department of Medicine, University of Ottawa; Ottawa Hospital Research Institute (Abdelaal, Parsons, Lapenskie, Yoo, Dhaliwal, Downar); Division of Medical Oncology (Srikanthan), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Supportive Care (al-Awamer, Mosher), Princess Margaret Cancer Centre, University Health Network; Division of Palliative Medicine (al-Awamer), Department of Medicine, University of Toronto; Division of Child and Adolescent Psychiatry (Mosher), Hospital for Sick Children, Toronto, Ont.; Bruyère Health Research Institute (Lapenskie, Fung); The Ottawa Hospital (Cleyn); ICES uOttawa (Yoo, Dhaliwal, Tanuseputro), Ottawa, Ont.; Department of Family Medicine and Primary Care (Tanuseputro), University of Hong Kong, Hong Kong.
Samantha YooDivision of Palliative Care (Abdelaal, Parsons, Downar), Department of Medicine, University of Ottawa; Ottawa Hospital Research Institute (Abdelaal, Parsons, Lapenskie, Yoo, Dhaliwal, Downar); Division of Medical Oncology (Srikanthan), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Supportive Care (al-Awamer, Mosher), Princess Margaret Cancer Centre, University Health Network; Division of Palliative Medicine (al-Awamer), Department of Medicine, University of Toronto; Division of Child and Adolescent Psychiatry (Mosher), Hospital for Sick Children, Toronto, Ont.; Bruyère Health Research Institute (Lapenskie, Fung); The Ottawa Hospital (Cleyn); ICES uOttawa (Yoo, Dhaliwal, Tanuseputro), Ottawa, Ont.; Department of Family Medicine and Primary Care (Tanuseputro), University of Hong Kong, Hong Kong.
Shan DhaliwalDivision of Palliative Care (Abdelaal, Parsons, Downar), Department of Medicine, University of Ottawa; Ottawa Hospital Research Institute (Abdelaal, Parsons, Lapenskie, Yoo, Dhaliwal, Downar); Division of Medical Oncology (Srikanthan), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Supportive Care (al-Awamer, Mosher), Princess Margaret Cancer Centre, University Health Network; Division of Palliative Medicine (al-Awamer), Department of Medicine, University of Toronto; Division of Child and Adolescent Psychiatry (Mosher), Hospital for Sick Children, Toronto, Ont.; Bruyère Health Research Institute (Lapenskie, Fung); The Ottawa Hospital (Cleyn); ICES uOttawa (Yoo, Dhaliwal, Tanuseputro), Ottawa, Ont.; Department of Family Medicine and Primary Care (Tanuseputro), University of Hong Kong, Hong Kong.
Peter TanuseputroDivision of Palliative Care (Abdelaal, Parsons, Downar), Department of Medicine, University of Ottawa; Ottawa Hospital Research Institute (Abdelaal, Parsons, Lapenskie, Yoo, Dhaliwal, Downar); Division of Medical Oncology (Srikanthan), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Supportive Care (al-Awamer, Mosher), Princess Margaret Cancer Centre, University Health Network; Division of Palliative Medicine (al-Awamer), Department of Medicine, University of Toronto; Division of Child and Adolescent Psychiatry (Mosher), Hospital for Sick Children, Toronto, Ont.; Bruyère Health Research Institute (Lapenskie, Fung); The Ottawa Hospital (Cleyn); ICES uOttawa (Yoo, Dhaliwal, Tanuseputro), Ottawa, Ont.; Department of Family Medicine and Primary Care (Tanuseputro), University of Hong Kong, Hong Kong.
James DownarDivision of Palliative Care (Abdelaal, Parsons, Downar), Department of Medicine, University of Ottawa; Ottawa Hospital Research Institute (Abdelaal, Parsons, Lapenskie, Yoo, Dhaliwal, Downar); Division of Medical Oncology (Srikanthan), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Supportive Care (al-Awamer, Mosher), Princess Margaret Cancer Centre, University Health Network; Division of Palliative Medicine (al-Awamer), Department of Medicine, University of Toronto; Division of Child and Adolescent Psychiatry (Mosher), Hospital for Sick Children, Toronto, Ont.; Bruyère Health Research Institute (Lapenskie, Fung); The Ottawa Hospital (Cleyn); ICES uOttawa (Yoo, Dhaliwal, Tanuseputro), Ottawa, Ont.; Department of Family Medicine and Primary Care (Tanuseputro), University of Hong Kong, Hong Kong.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdolescents and young adults (AYAs) with cancer often experience high-intensity end-of-life care and low utilization of palliative care. To explore this further, we evaluated the frequency of palliative care involvement and its association with end-of-life care intensity among AYAs with cancer in Ontario, Canada.

methodsWe conducted a retrospective cohort study using health administrative databases in Ontario, Canada, from Jan. 1, 2018, to Dec. 31, 2022. The cohort included AYA cancer decedents, aged 15 to 39 years. We categorized palliative care involvement into lifetime involvement and involvement in the last 90 days of life. We classified palliative care according to whether it was provided by a generalist or specialist physician using previously validated criteria. The primary outcome was the prevalence of palliative care involvement. Secondary outcomes included various measures of the intensity of end-of-life care; we analyzed whether palliative care involvement was associated with intensity of end-of-life care.

resultsAmong 1981 AYAs, 76% had palliative care involvement in the last 90 days of life, of which 89% were from specialist palliative care physicians. Specialist palliative care involvement was associated with higher rates of hospital admission (58% v. 57% v. 47%,

interpretationBoth palliative care and intensive care are increasingly used among AYAs with cancer at the end of life in Ontario, Canada. Increasing the availability of specialized AYA-focused palliative care may help to optimize end-of-life care in this population.

Indexed as

NeoplasmsPalliative CareTerminal CareAdolescentAdultFemaleHumansMaleOntarioRetrospective StudiesYoung Adult

Identifiers

PMID41326042
PMCPMC12680387

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.