Evidence map›Paper›PMID 41326008›Full record

ArticleJournal of proteome research2026

The Omics Molecule Extractor: A Web Application for the Selection of Potential Biomarker Panels.

Emanuel Lange, Kay Schallert, Johannes Schwerdt, Susmita Ghosh, Andreas Hentschel, Yvonne Reinders, Robert Heyer

Abstract read
In one paragraph

Article in Journal of proteome research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emanuel LangeLeibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund 44139, Germany.ORCID 0009-0008-6620-6681
Kay SchallertLeibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund 44139, Germany.
Johannes SchwerdtHochschule Merseburg, Merseburg 06217, Germany.
Susmita GhoshLeibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund 44139, Germany.
Andreas HentschelLeibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund 44139, Germany.
Yvonne ReindersLeibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund 44139, Germany.
Robert HeyerLeibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund 44139, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selecting molecular panels that are applicable to classify the health state of patients is a common task in omics data analysis. Existing software for molecule selection lacks features to select molecule panels from large data sets, requires programming experience, or lacks user-friendly interfaces. We present the Omics Molecule Extractor (OMEx), an open-source web application providing a user-friendly workflow for selecting molecules and molecule panels for sample classification from large data sets. OMEx's user interface provides interactive visualization for exploring input data and analysis results. The feature selection strategy underlying the algorithm is based on machine learning and has not been available in any software with a user interface. Extensive testing using synthetic data sets with known ground truth showed that the algorithm discovers group-separating molecules with high precision. Additionally, OMEx was tested on five real-world omics data sets, demonstrating high reproducibility and overlap with reported molecules from other feature selection methods, while also reporting alternative molecules of interest. OMEx is freely available at https://mdoa-tools.bi.denbi.de/omex/home.

Indexed as

BiomarkersProteomicsSoftwareAlgorithmsHumansInternetMachine LearningUser-Computer InterfaceBiomarkersbiomarkersfeature selectionmachine learningmultiomicspatient classification

Identifiers

PMID41326008
PMCPMC12772118

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.