Evidence map›Paper›PMID 41325964›Full record

ArticleJournal of minimally invasive gynecology2026

Cost-Effectiveness of Combined Minimally Invasive Hysterectomy and Bariatric Surgery in Women With Morbid Obesity and Endometrial Hyperplasia or Early-Stage Endometrial Cancer.

Jo'an Tankou, Lisa M Pollack, Elise Wilson, Iris Kuo, Mei Wang, Shaina R Eckhouse, Su-Hsin Chang, Andrea R Hagemann

Abstract read
In one paragraph

Article in Journal of minimally invasive gynecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jo'an TankouDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Barnes-Jewish Hospital, Washington University in St. Louis School of Medicine (Drs. Tankou and Wilson), St. Louis, Missouri.
Lisa M PollackDivision of Public Health Sciences, Department of Surgery, Washington University in St. Louis School of Medicine (Drs. Pollack, Wang, and Chang), St. Louis, Missouri. Electronic address: lpollack@wustl.edu.
Elise WilsonDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Barnes-Jewish Hospital, Washington University in St. Louis School of Medicine (Drs. Tankou and Wilson), St. Louis, Missouri.
Iris KuoWashington University in St. Louis School of Medicine (Drs. Kuo and Hagemann), St. Louis, Missouri.
Mei WangDivision of Public Health Sciences, Department of Surgery, Washington University in St. Louis School of Medicine (Drs. Pollack, Wang, and Chang), St. Louis, Missouri.
Shaina R EckhouseSection of Minimally Invasive Surgery, Department of Surgery, Washington University School of Medicine (Dr. Eckhouse), St. Louis, Missouri.
Su-Hsin ChangDivision of Public Health Sciences, Department of Surgery, Washington University in St. Louis School of Medicine (Drs. Pollack, Wang, and Chang), St. Louis, Missouri.
Andrea R HagemannWashington University in St. Louis School of Medicine (Drs. Kuo and Hagemann), St. Louis, Missouri.

Funding

Route 66 Endometrial Cancer SPOREP50CA265793 · NCI · WASHINGTON UNIVERSITY · PI Esther Jiaxin Lu · 2023 to 2026
$11.6M
NCI NIH HHS P50 CA265793
6 · The paper itself

Abstract

STUDY

objectiveWe studied the cost-effectiveness of simultaneous bariatric surgery and minimally invasive hysterectomy (MIH) (combined surgery) in comparison to MIH alone in endometrial cancer (EC) survivors with obesity-related disease (ORD).

designCost-effectiveness analysis.

settingHypothetical cohort of women aged 50 to 69 with obesity (BMI ≥ 30 kg/m

interventionsCombined surgery vs MIH alone. MEASUREMENTS AND MAIN

resultsWe constructed a decision-analytic model with lifetime horizon to compare life expectancy and lifetime healthcare costs between patients with combined surgery and those with MIH alone. Utility weights, a measure of health states that affect quality of life, from published studies were used to calculate quality-adjusted life years (QALYs). Lifetime healthcare costs associated with ORD and costs for MIH and surgical complications were obtained from published studies. Costs for combined surgery were obtained from a single institution. All costs were evaluated from the healthcare sector perspective and presented in US dollars at the 2022 price level. Future costs and QALYs were discounted to present values using an annual rate of 3%. For the 50 to 59 age group, QALYs for combined surgery were 14.8 compared with 11.0 for MIH alone. The lifetime healthcare cost for patients with combined surgery was $186 124 compared with $335 995 for MIH alone. For the 60 to 69 age group, QALYs for combined surgery were 12.0 compared with 7.9 for MIH alone. The lifetime healthcare cost for patients with combined surgery was $155 451 compared with $273 403 for MIH alone. Combined surgery yielded higher QALYs and lower costs than MIH alone.

conclusionFor women with endometrial intraepithelial neoplasia or early-stage EC with obesity and ORD, combined surgery may represent a cost-saving and QALYs-improving option for treatment. However, barriers to this approach may be insurmountable.

Indexed as

Bariatric SurgeryEndometrial HyperplasiaEndometrial NeoplasmsHysterectomyObesity, MorbidAgedCost-Benefit AnalysisFemaleHumansMiddle AgedQuality-Adjusted Life YearsBariatric surgeryCost-effectivenessEndometrial cancerMinimally invasive hysterectomyObesity

Identifiers

PMID41325964
PMCPMC13082198

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.