Evidence map›Paper›PMID 41325753›Full record

ArticleExperimental physiology2025

Cerebral oxygen extraction across different exercise intensities: Role of arterial

L Madden Brewster, Travis Dylan Gibbons, Hannah Grace Caldwell, Connor A Howe, Jennifer S Duffy, Andrew R Steele, Justin A Monteleone, Jay M J R Carr, Jodie Lauren Koep, Tenasia D R Monaghan and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

L Madden BrewsterCentre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia, Kelowna, British Columbia, Canada.ORCID https://orcid.org/0000-0002-5571-4268
Travis Dylan GibbonsDepartment of Biological Sciences, College of the Environment, Forestry, and Natural Sciences, Northern Arizona University, Flagstaff, Arizona, USA.ORCID https://orcid.org/0000-0003-3893-9948
Hannah Grace CaldwellCentre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia, Kelowna, British Columbia, Canada.ORCID https://orcid.org/0000-0001-6072-7277
Connor A HoweCentre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia, Kelowna, British Columbia, Canada.ORCID https://orcid.org/0000-0002-1133-2444
Jennifer S DuffyCentre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia, Kelowna, British Columbia, Canada.
Andrew R SteeleCentre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia, Kelowna, British Columbia, Canada.ORCID https://orcid.org/0000-0003-0557-847X
Justin A MonteleoneCentre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia, Kelowna, British Columbia, Canada.
Jay M J R CarrCentre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia, Kelowna, British Columbia, Canada.
Jodie Lauren KoepCentre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia, Kelowna, British Columbia, Canada.
Tenasia D R MonaghanCentre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia, Kelowna, British Columbia, Canada.
David B MacLeodDepartment of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA.ORCID https://orcid.org/0000-0002-5989-3961
Philip N AinslieCentre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia, Kelowna, British Columbia, Canada.

Funding

Natural Sciences and Engineering Research Council of Canada Discovery Grant
6 · The paper itself

Abstract

Stability in cerebral oxygen extraction fraction (OEF) is typically determined by alterations in cerebral blood flow (CBF). At rest, arterial partial pressure of carbon dioxide (

Indexed as

cerebralexerciseoxygen extraction

Identifiers

PMID41325753
PMCPMC13395019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.