ArticleJMIR research protocols2025
Cocreation of a Mobile App (AYABytes) by Physicians and Adolescents and Young Adults With Cancer to Improve Access to Cancer-Related Resources and Reduce Distress: Protocol for a Single-Arm Feasibility Study.
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Abstract
backgroundAdolescents and young adults with cancer require dedicated and tailored management that bridges adult and pediatric oncology services. At the National Cancer Centre Singapore, 40% of newly diagnosed adolescents and young adults report significant distress due to uncertainty about prognosis, treatment, and disruption of life milestones. A major unmet need is access to reliable, age-appropriate information. Prior studies demonstrate that digital technology can effectively deliver such support.
objectiveThis study describes the protocol for evaluating AYABytes (Adolescent and Young Adult Building Youths, a Technology for Education and Sharing), a mobile app cocreated by patients and health care professionals to improve health-related quality of life for adolescent and young adult oncology patients. An iterative information-gathering process was conducted, including semistructured interviews with 2 clinicians, 3 cancer survivors, and 3 care partners to cocreate this mobile app. AYABytes is an interactive, phone-based intervention designed to engage adolescent and young adult oncology patients with personalized education, mood, and symptom self-management resources with an inbuilt algorithm that responds to patient-reported questionnaires.
methodsThe app will be evaluated in 2 phases-a pilot test and an implementation test. In the pilot test, the app will be launched to a test group of 20 adolescent and young adult oncology patients aged between 16 and 45 years, selected for representation among the age group and their malignancies. Patients will be allowed to use the app for 1 month. Feasibility and acceptability were assessed via a semistructured survey. In the implementation stage, 200 patients will be allowed to use the app over 6 months and will complete an EQ-5D-5L questionnaire at baseline and at the 1- and 6-month marks. Evaluation of the mobile app was performed via the mHealth App Usability Questionnaire at similar intervals.
resultsFunding for the development and trial of AYABytes was awarded in October 2020 through a National Cancer Centre Singapore research grant. Pilot testing was completed in May 2024. The implementation phase began in June 2024 and is currently ongoing.
conclusionsWe believe that AYABytes, a novel eHealth mobile app, will be both beneficial and easily used by adolescent and young adult oncology patients. Evaluating the app and its quantifiable impact on improving the quality of life of adolescent and young adult oncology patients will help enrich the evidence for mobile health interventions. It will also validate new digital approaches to help adolescent and young adult oncology patients reduce their distress and address unmet needs and concerns. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/69453.
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