Evidence map›Paper›PMID 41325580›Full record

SynthesisBlood transfusion = Trasfusione del sangue

Optimizing platelet transfusion thresholds in preterm infants: a systematic review and narrative synthesis of impacts on survival and neurodevelopment.

Dengjun Liu, Qian Gao, Jogender Kumar, Yan Yue, Jing Shi, Jun Tang, Tao Xiong

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Blood transfusion = Trasfusione del sangue. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dengjun LiuDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Qian GaoDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Jogender KumarDepartment of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Yan YueDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Jing ShiDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Jun TangDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Tao XiongDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this analysis was to evaluate the impact of different platelet transfusion thresholds on short-term and long-term outcomes in preterm infants, and to inform evidence-based, individualized transfusion strategies. MATERIALS AND

methodsPubMed, Embase, and the Cochrane Library (database initiation until December 2024) were searched. Comparative studies of restrictive transfusion strategies vs liberal transfusion strategies in thrombocytopenic neonates were included. The review protocol was prospectively registered (CRD42020169262).

resultsOf 4,102 reports screened, three randomized controlled trials and two cohort studies were included (1,851 patients). Restrictive transfusion strategies did not increase short-term adverse events and may potentially reduce the incidence of mortality and severe neurodevelopmental impairment at 2 years corrected age. DISCUSSION: Restrictive platelet transfusion thresholds (25×10

Indexed as

Infant, PrematureNeurodevelopmental DisordersPlatelet TransfusionHumansInfantInfant, Newborn

Identifiers

PMID41325580
PMCPMC12860587

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.