Evidence map›Paper›PMID 41325529›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

An Archean atmosphere rich in sulfur biomolecules.

Nathan W Reed, Cade M Christensen, Jason D Surratt, Shawn Erin McGlynn, Boswell A Wing, Cajetan Neubauer, Margaret A Tolbert, Eleanor C Browne

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. An Archean atmosphere rich in sulfur biomolecules.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nathan W ReedDepartment of Chemistry, University of Colorado Boulder, Boulder, CO 80309.ORCID 0000-0002-0401-5993
Cade M ChristensenDepartment of Chemistry, College of Arts and Sciences, University of North Carolina at Chapel Hill, NC 27514.ORCID 0009-0002-7663-2736
Jason D SurrattDepartment of Chemistry, College of Arts and Sciences, University of North Carolina at Chapel Hill, NC 27514.ORCID 0000-0002-6833-1450
Shawn Erin McGlynnCooperative Institute for Research in Environmental Sciences, University of Colorado Boulder, Boulder, CO 80309.ORCID 0000-0002-8199-7011
Boswell A WingDepartment of Geological Sciences, University of Colorado Boulder, Boulder, CO 80309.ORCID 0000-0002-8962-5183
Cajetan NeubauerDepartment of Geological Sciences, University of Colorado Boulder, Boulder, CO 80309.ORCID 0000-0002-5348-5609
Margaret A TolbertDepartment of Chemistry, University of Colorado Boulder, Boulder, CO 80309.ORCID 0000-0001-5730-6412
Eleanor C BrowneDepartment of Chemistry, University of Colorado Boulder, Boulder, CO 80309.ORCID 0000-0002-8076-9455

Funding

DOC | National Oceanic and Atmospheric Administration (NOAA) NA22OAR4320151MEXT | Japan Society for the Promotion of Science (JSPS) JP22H01343NASA (NASA) 80NSSC20K0232NASA (NASA) 80NSSC23K1357NASA (NASA) 80NSSC23K1526NASA | NASA Postdoctoral Program (NPP) AstrobiologyNSF (NSF) 1724300NSF (NSF) 1724393NSF (NSF) 2039788
6 · The paper itself

Abstract

The abiotic production of sulfur-containing biomolecules under mild and globally relevant conditions has been an elusive endeavor in prebiotic chemistry experiments. As a result, a disconnect has emerged between understanding the origins of life and the later stages of biological evolution; the former potentially occurred independent of sulfur while the latter is universally dependent on it. Here, we demonstrate that planetary organic haze chemistry produces a suite of sulfur biomolecules including cysteine, coenzyme M, taurine, and potentially methionine and homocysteine. These compounds may form high in the atmosphere and subsequently deposit to early surface environments in sufficient amounts to support a budding global biosphere. Our findings thus challenge long-standing assumptions that sulfur biomolecules such as cysteine must have been biological "inventions."

Indexed as

AtmosphereSulfurOrigin of LifeSulfurbiomolecule deliveryearly Earthplanetary atmospheresprebiotic chemistrysulfur biomolecules

Identifiers

PMID41325529
PMCPMC12704708

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.