Evidence map›Paper›PMID 41325490›Full record

ArticlePloS one2025

Protocol for a randomized controlled trial of a combined motivational interviewing and behavioral couples therapy intervention to reduce intimate partner violence and alcohol use in south India.

Meghna Achar, Megan Ramaiya, Krishnamachari Srinivasan, Maria L Ekstrand, Elsa Heylen, Johnson Pradeep R, Miriam Hartmann, Nisha C K, Matilda Pereira, Bibhav Acharya

Abstract readClinical Trial Protocol
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Meghna AcharDivision of Mental Health and Neurosciences, St. John's Research Institute, St. John's Medical College, Bengaluru, Karnataka, India.ORCID https://orcid.org/0000-0002-3724-9868
Megan RamaiyaDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, California, United States of America.ORCID https://orcid.org/0000-0003-1489-0991
Krishnamachari SrinivasanDivision of Mental Health and Neurosciences, St. John's Research Institute, St. John's Medical College, Bengaluru, Karnataka, India.
Maria L EkstrandDivision of Mental Health and Neurosciences, St. John's Research Institute, St. John's Medical College, Bengaluru, Karnataka, India.
Elsa HeylenDepartment of Medicine, Division of Prevention Science, University of California, San Francisco, California, United States of America.
Johnson Pradeep RDivision of Mental Health and Neurosciences, St. John's Research Institute, St. John's Medical College, Bengaluru, Karnataka, India.
Miriam HartmannWomen's Global Health Imperative, RTI, Berkeley, California, United States of America.
Nisha C KDepartment of Psychiatry, St. John's Medical College Hospital, St. John's Medical College, Bengaluru, Karnataka, India.
Matilda PereiraDivision of Mental Health and Neurosciences, St. John's Research Institute, St. John's Medical College, Bengaluru, Karnataka, India.
Bibhav AcharyaDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, California, United States of America.

Funding

A combined motivational interviewing and behavioral couples therapy intervention to reduce intimate partner violence and alcohol use in South IndiaR01AA029303 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Bibhav Acharya, Maria L. Ekstrand · 2022 to 2026
$3.3M
NIAAA NIH HHS R01 AA029303
6 · The paper itself

Abstract

There is a strong association between alcohol use disorder (AUD) and intimate partner violence (IPV), both widely prevalent global health issues. However, few interventions target both IPV and AUD, include both partners in the intervention, and are delivered by non-specialist providers in low- and middle-income country (LMIC) settings with scarce mental health resources. This paper describes the protocol for a randomized controlled trial of a combined motivational interviewing (MI) and behavioral couples therapy (BCT) intervention delivered in urban primary care settings in India by nurses with no behavioral health training prior to joining the study. A total of 400 couples will be enrolled and randomized to one of two arms: an intervention arm comprised of 10, hour-long sessions of the MI + BCT intervention, and a control arm receiving enhanced usual care and medical-legal referrals. Data collection will take place at five timepoints: baseline (pre-intervention), three-, six-, nine-, and 12-month follow-ups. Primary quantitative outcomes include the frequency of intimate partner violence over the last 6 months and self-reported quantity and frequency of alcohol use, drinking behaviors, and alcohol-related problems as assessed on the Alcohol Use Disorders Identification Test (AUDIT). Secondary outcomes include number of days with a negative breathalyzer test over a one-week period, communication patterns, and the quality of marital relationship. Qualitative interviews with a sub-sample (n = 40 couples) from the intervention arm will take place immediately post-intervention and at 12 months to explore underlying mechanisms of change. If successful, study results can inform future efforts to develop scalable interventions for IPV and AUD that can be sustained in the Indian public health system through existing PHC staff and infrastructure and be adapted to similar sociocultural settings.

Indexed as

Alcohol DrinkingAlcoholismBehavior TherapyCouples TherapyIntimate Partner ViolenceMotivational InterviewingAdultFemaleHumansIndiaMaleRandomized Controlled Trials as Topic

Identifiers

PMID41325490
PMCPMC12668616

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.