ReviewBrain : a journal of neurology2026
RNArchitects: how hnRNPs shape neuronal landscapes.
Review in Brain : a journal of neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- From development to disease: the neuronal role of hnRNPs through the lens ofFrontiers in cell and developmental biology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Neurons rely on finely tuned RNA regulatory mechanisms to sustain their specialized functions, with heterogeneous nuclear ribonucleoproteins (hnRNPs) emerging as key regulators of these processes. hnRNPs exert multilayered control over synaptic plasticity, axonal function, and neurodevelopmental gene expression by dynamically coordinating mRNA splicing, stability, transport and local translation. Given their pivotal role in neuronal RNA metabolism, recent discoveries have highlighted how hnRNP dysfunction drives pathological RNA dysregulation across a spectrum of neurological disorders. This review provides insights into hnRNP-mediated RNA regulation in the brain, examines their contributions to neurological diseases, and explores how targeting these proteins could pave the way for novel therapeutic strategies to preserve neuronal integrity across diverse neurological conditions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.