Evidence map›Paper›PMID 41324899›Full record

ArticleTechnology in cancer research & treatment

Total Neoadjuvant Therapy with Induction FOLFIRINOX and Concurrent Chemoradiation for Locally Advanced Lower-Middle Rectal Cancer: A retrospective study in Vietnam.

Hung Van Nguyen, Huy Le Trinh, Ngoc Dung Tran, Manh Duy Pham, Duc Khac Duong, Linh Thuy Duong, Thi Hoan Pham, Huyen Thi Phan, Trung Bach Tran, Hau Xuan Nguyen

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Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hung Van NguyenDepartment of Oncology, Hanoi Medical University, Hanoi, Vietnam.ORCID 0000-0002-8240-3641
Huy Le TrinhDepartment of Oncology, Hanoi Medical University, Hanoi, Vietnam.ORCID 0000-0001-9598-5962
Ngoc Dung TranDepartment of Coloproctology and Pelvic Floor Surgery, Hanoi Medical University Hospital, Hanoi, Vietnam.
Manh Duy PhamDepartment of Oncology, Hanoi Medical University, Hanoi, Vietnam.
Duc Khac DuongDepartment of Oncology, Hanoi Medical University, Hanoi, Vietnam.
Linh Thuy DuongDepartment of Radiation, Military 103 Hospital, Hanoi, Vietnam.
Thi Hoan PhamDepartment of Radiation, Military 103 Hospital, Hanoi, Vietnam.
Huyen Thi PhanDepartment of Pathology, Hanoi Medical University Hospital, Hanoi, Vietnam.
Trung Bach TranDepartment of Oncology, Hanoi Medical University, Hanoi, Vietnam.
Hau Xuan NguyenDepartment of Oncology, Hanoi Medical University, Hanoi, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionLocally advanced rectal cancer (LARC) remains a therapeutic challenge, with significant risks of both locoregional and distant relapse. Total neoadjuvant therapy (TNT), which combines induction chemotherapy and chemoradiotherapy (CRT) prior to surgery, has emerged as a potentially more effective strategy than traditional approaches, yet data from low- and middle-income countries (LMICs) remain limited. This study evaluates the efficacy and toxicity of induction FOLFIRINOX followed by concurrent CRT in Vietnamese patients with lower-middle LARC.MethodsA retrospective analysis was conducted on adult patients (

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsChemoradiotherapyNeoadjuvant TherapyRectal NeoplasmsAdultAgedCombined Modality TherapyFemaleFluorouracilHumansInduction ChemotherapyIrinotecanLeucovorinMaleMiddle AgedNeoplasm StagingFluorouracilfolfirinoxIrinotecanLeucovorinOxaliplatinFOLFIRINOXLMIClocally advanced rectal cancertotal neoadjuvant therapyVietnam

Identifiers

PMID41324899
PMCPMC12669481

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.