SynthesisJournal of youth and adolescence2026
Substance Use and Non-Suicidal Self-Injury among Adolescents: A Meta-Analysis of Association Patterns and Moderating Factors.
Synthesis in Journal of youth and adolescence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Though previous meta-analyses on the relation between adolescent substance use and non-suicidal self-injury (NSSI) represent important steps toward a better understanding of these typically co-emergent behaviors, their findings remain limited by either broad or select substance type foci, as well as incomplete examination of potentially neglected moderators. This meta-analysis examined associations between substance use and NSSI among a large sample size of adolescents (N = 1,191,255) across 18 studies published between 2007 and 2024. Results revealed moderate positive associations between substance use and NSSI (OR = 1.79, 95% CI [1.39, 2.31]). Stimulants showed the strongest association (OR = 1.93), followed by hallucinogens (OR = 1.76) and depressants (OR = 1.71). Study design (cross-sectional vs. longitudinal) and measurement approaches (categorical vs. continuous vs. combined) moderated some associations, and geographic variations were observed. However, the extremely high heterogeneity across studies (I²>94%) indicates substantial complexity in these relationships that warrants cautious interpretation. These findings reveal how consistent associations across substance types, with stimulants displaying a notably stronger association, suggest shared vulnerabilities during adolescence and possibly common emotion dysregulation mechanisms; clarify the role of region and type of NSSI variable as key moderators with respect to specific substance types; and advance developmental research by clarifying how NSSI and substance use co-develop during adolescence.
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