Evidence map›Paper›PMID 41324850›Full record

ArticleIntensive care medicine experimental2025

Ultrasound monitoring of skeletal muscle wasting and relation to nutritional intervention in critically ill patients: MUScleNut study.

Catarina Rosa Domingues, Simão C Rodeia, Ana Rita Francisco, Laura Santos, Carolina Cerca, Madalena Costa, Vera Pinto, Philip Fortuna, Ana Brito-Costa, Luís Bento

Abstract read
In one paragraph

Article in Intensive care medicine experimental, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Catarina Rosa DominguesIntensive Care Medicine Department, Hospital de São José, Unidade Local de Saúde São José, Lisboa, Portugal. catarinarosadomingues@gmail.com.ORCID http://orcid.org/0000-0002-3306-8912
Simão C RodeiaIntensive Care Medicine Department, Hospital de São José, Unidade Local de Saúde São José, Lisboa, Portugal.
Ana Rita FranciscoIntensive Care Medicine Department, Hospital de São José, Unidade Local de Saúde São José, Lisboa, Portugal.
Laura SantosIntensive Care Medicine Department, Hospital de São José, Unidade Local de Saúde São José, Lisboa, Portugal.
Carolina CercaIntensive Care Medicine Department, Hospital de São José, Unidade Local de Saúde São José, Lisboa, Portugal.
Madalena CostaIntensive Care Medicine Department, Hospital de São José, Unidade Local de Saúde São José, Lisboa, Portugal.
Vera PintoCentro de Estatística E Aplicações (CEAUL), Faculdade de Ciências, Universidade de Lisboa, Lisboa, Portugal.
Philip FortunaIntensive Care Medicine Department, Hospital de São José, Unidade Local de Saúde São José, Lisboa, Portugal.
Ana Brito-CostaNutrition Unit, Hospital de São José, Unidade Local de Saúde São José, Lisboa, Portugal.
Luís BentoIntensive Care Medicine Department, Hospital de São José, Unidade Local de Saúde São José, Lisboa, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCritically ill patients frequently experience profound skeletal muscle (SM) wasting, to which early detection and effective clinical management remain significant challenges. Ultrasonography (US) provides early objective information about SM compared with usual functional tests. The characteristics of the optimal nutritional support are controversial. This observational study aimed to characterize the SM changes through US in the first week after Intensive Care Unit (ICU) admission and to evaluate the potential interference factors with a focus on nutritional support.

resultsA total of 95 patients (age 55.7 ± 16.01 years, 70.5% male) were included. All the ultrasound SM measures tendentially reduced after admission: quadriceps muscle layer thickness (QMLT) 10.03% (0.38 ± 0.73 cm), rectus femoris cross-sectional area (RF-CSA) 10.48% (0.50 ± 1.38 cm

conclusionPresent findings demonstrate a marked reduction in the SM ultrasound measures evaluated in the first week after ICU admission, mainly in patients at nutritional risk. More evidence on optimal nutritional strategies to attenuate SM wasting is warranted.

Indexed as

Intensive careIntensive care unit acquired weaknessMuscle wastingNutritionUltrasound

Identifiers

PMID41324850
PMCPMC12669447

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.