Evidence map›Paper›PMID 41324709›Full record

ArticleEuropean journal of nutrition2025

The relationship between the EAT-Lancet dietary pattern and risk of cardiovascular events in patients with established cardiovascular disease.

Lukas L F Hoes, Chiara Colizzi, Yvonne T van der Schouw, Johanna M Geleijnse, Jannick A N Dorresteijn, Manon G van der Meer, Martin Teraa, Frank L J Visseren, Charlotte Koopal

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Article in European journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Lukas L F HoesDepartment of Vascular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Chiara ColizziJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Yvonne T van der SchouwJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Johanna M GeleijnseDivision of Human Nutrition and Health, Wageningen University and Research, Wageningen, Netherlands.
Jannick A N DorresteijnDepartment of Vascular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Manon G van der MeerDepartment of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Martin TeraaDepartment of Vascular Surgery, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Frank L J VisserenDepartment of Vascular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. F.L.J.Visseren@umcutrecht.nl.
Charlotte KoopalDepartment of Vascular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

Funding

Regio Deal Foodvalley 162135
6 · The paper itself

Abstract

purposeTo reduce the risk of recurrent cardiovascular events in patients with established cardiovascular disease (CVD), guidelines recommend adopting a more plant-based diet. The EAT-Lancet diet, which focuses on plant-based foods, is associated with a lower risk of CVD in apparently healthy people. However, the relationship in patients with established CVD is unclear. Therefore, the aim of this research was to quantify the relationship between the EAT-Lancet Healthy Reference Diet (HRD) and risk of recurrent CVD in patients with established CVD.

methodsPatients with established CVD from the Utrecht Cardiovascular Cohort-Second Manifestations of ARTerial disease were studied. Dietary intake was measured using a food frequency questionnaire and the relationship between the EAT-Lancet HRD (score from 0 to 140 points) and non-fatal myocardial infarction and stroke was assessed using Cox regression adjusted for age, sex, educational background, lifestyle factors, and energy intake.

resultsDuring a follow-up of 24,212 person-years 209 non-fatal vascular events occurred. The median score for the EAT-Lancet HRD was 57 out of 140 points (IQR: 41-68). After adjustment for confounders, a diet more in line with the EAT-Lancet HRD was associated with a lower risk of non-fatal vascular events (HR 0.87 (95% CI 0.79-0.96) per 10-point increase); stroke (HR 0.76 (95% CI 0.63-0.91) per 10-point increase); and a trend towards lower risk of myocardial infarction (HR 0.90 (95% CI 0.81-1.02) per 10-point increase).

conclusionIn patients with established CVD, a dietary pattern more in line with the EAT-Lancet HRD is associated with a lower risk of non-fatal stroke and myocardial infarction.

Indexed as

Cardiovascular DiseasesDietDiet, HealthyDiet, VegetarianAgedCohort StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedMyocardial InfarctionNetherlandsProportional Hazards ModelsRisk FactorsStrokeCerebrovascular accidentCoronary artery diseaseLifestylePlant-based dietSecondary preventionVegetarian diet

Identifiers

PMID41324709
PMCPMC12669304

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.