Evidence map›Paper›PMID 41324689›Full record

ReviewSkeletal radiology2026

Dual-energy CT for detection of knee fractures as alternative to MRI.

Giovanni Foti, Gianluca Tripodi, Giuseppe Ocello, Alessandro Spezia, Leonardo Monterubbiano, Christian Booz, Guglielmo Manenti, Flavio Spoto

Abstract readReview
PubMed Publisher
In one paragraph

Review in Skeletal radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giovanni FotiDepartment of Radiology, IRCCS Sacro Cuore Hospital, Via Don A. Sempreboni 10. 37024, Negrar, Italy. gfoti81@yahoo.it.ORCID http://orcid.org/0000-0002-1426-2402
Gianluca TripodiDepartment of Radiology, Policlinico G. Martino, Messina, Italy.
Giuseppe OcelloDepartment of Radiology, Policlinico G. Martino, Messina, Italy.
Alessandro SpeziaDepartment of Radiology, Policlinico Universitario GB Rossi, Verona, Italy.
Leonardo MonterubbianoDepartment of Radiology, IRCCS Sacro Cuore Hospital, Via Don A. Sempreboni 10. 37024, Negrar, Italy.
Christian BoozDepartment of Diagnostic and Interventional Radiology, Division of Experimental Imaging, University Hospital Frankfurt, Frankfurt Am Main, 60596, Germany.
Guglielmo ManentiDepartment of Diagnostic Imaging, Molecular Imaging, Interventional Radiology and Radiation Therapy "Tor Vergata", Rome, Italy.
Flavio SpotoDepartment of Radiology, IRCCS Sacro Cuore Hospital, Via Don A. Sempreboni 10. 37024, Negrar, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dual-energy CT (DECT) has emerged as a valuable imaging modality in musculoskeletal radiology, offering unique capabilities through virtual non-calcium reconstructions and spectral analysis. This narrative review examines the current evidence and clinical applications of DECT as an alternative to MRI in acute knee trauma evaluation. We discussed the technical principles of DECT, including virtual non-calcium imaging for bone marrow edema detection, metal artifact reduction techniques, and soft tissue assessment capabilities. The review covers six key clinical applications: complex fractures with articular involvement, subtle impacted fractures, stress fractures and healing assessment, imaging around metallic implants, osteochondritis dissecans evaluation, fracture assessment in specific knee locations. Current evidence indicates that DECT can detect bone marrow edema with sensitivity and specificity comparable to MRI, while providing distinct advantages in availability, acquisition speed, and compatibility with metallic implants. The advent of photon-counting CT technology is expected to further enhance both spatial resolution and spectral differentiation. Although MRI remains the gold standard for comprehensive assessment of knee trauma, DECT offers a practical alternative in selected clinical scenarios-particularly in emergency settings and in patients with contraindications to MRI. Future studies should aim to standardize acquisition protocols and establish evidence-based guidelines to support its optimal clinical application.

Indexed as

Knee FracturesKnee InjuriesMagnetic Resonance ImagingRadiography, Dual-Energy Scanned ProjectionTomography, X-Ray ComputedHumansSensitivity and SpecificityDual-energy CTEdemaFractureKneeMRITrauma

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.