Evidence map›Paper›PMID 41324588›Full record

ArticleACS applied materials & interfaces2025

Cell-Driven Encapsulation of Chlorophyllin-Based Carbon Dots within Exosomes for Enhanced Photodynamic Therapy: miRNA Profiling Reveals Mechanistic Insights.

Omur Besbinar, Recep Uyar, Emel Kirbas Cilingir, Ana Martín-Pardillos, Jose L Hueso, Ahmet Ceylan, Ozge Ozgenc, Okan Ekim, Mehmet Altay Unal, Fikret Ari and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Omur BesbinarStem Cell Institute, Ankara University, 06520 Ankara, Turkey.
Recep UyarStem Cell Institute, Ankara University, 06520 Ankara, Turkey.
Emel Kirbas CilingirDepartment of Chemistry, University of Miami, 1301 Memorial Drive, Coral Gables, Florida 33146, United States.
Ana Martín-PardillosInstituto de Nanociencia y Materiales de Aragon (INMA), CSIC-Universidad de Zaragoza, Campus Rio Ebro, Edificio I+D, C/Poeta Mariano Esquillor, s/n, 50018 Zaragoza, Spain.
Jose L HuesoInstituto de Nanociencia y Materiales de Aragon (INMA), CSIC-Universidad de Zaragoza, Campus Rio Ebro, Edificio I+D, C/Poeta Mariano Esquillor, s/n, 50018 Zaragoza, Spain.ORCID 0000-0002-4546-4111
Ahmet CeylanDepartment of Histology Embryology, Faculty of Veterinary Medicine, Ankara University, 06110 Ankara, Turkey.
Ozge OzgencDepartment of Histology Embryology, Faculty of Veterinary Medicine, Ankara University, 06110 Ankara, Turkey.
Okan EkimDepartment of Anatomy, Faculty of Veterinary Medicine, Ankara University, 06110 Ankara, Turkey.
Mehmet Altay UnalStem Cell Institute, Ankara University, 06520 Ankara, Turkey.ORCID 0000-0001-8607-5043
Fikret AriDepartment of Electrical Electronic Engineering, Faculty of Engineering, 06830 Ankara, Turkey.
Roger M LeblancDepartment of Chemistry, University of Miami, 1301 Memorial Drive, Coral Gables, Florida 33146, United States.ORCID 0000-0001-8836-8042
Jesus SantamariaInstituto de Nanociencia y Materiales de Aragon (INMA), CSIC-Universidad de Zaragoza, Campus Rio Ebro, Edificio I+D, C/Poeta Mariano Esquillor, s/n, 50018 Zaragoza, Spain.ORCID 0000-0002-8701-9745
Acelya YilmazerStem Cell Institute, Ankara University, 06520 Ankara, Turkey.ORCID 0000-0003-2712-7450

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes, nanoscale extracellular vesicles, have emerged as promising carriers in drug delivery due to their ability to bypass biological barriers, low toxicity, high stability, and intrinsic targeting capabilities. Mesenchymal stem-cell-derived exosomes (EXO

Indexed as

CarbonChlorophyllidesExosomesMicroRNAsPhotochemotherapyPhotosensitizing AgentsQuantum DotsCell Line, TumorGlioblastomaHumansMesenchymal Stem CellsCarbonChlorophyllideschlorophyllinMicroRNAsPhotosensitizing Agentscarbon dotsdrug deliveryexosomesmiRNA profilingphotodynamic therapy

Identifiers

PMID41324588
PMCPMC12874207

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.