Evidence map›Paper›PMID 41324173›Full record

ArticleJournal of primary care & community health

A Theory Informed Multi-Component Intervention to Promote Family Medicine Provider PrEP Prescription to Adolescent Girls and Young Women in the U.S. Southeast: Pilot Trial Results.

Lynn T Matthews, Madeline C Pratt, Oluwaseyi O Isehunwa, Lillian M Klasen, Samantha V Hill, Tina Simpson, Brook A Hubner, Nicholas Van Wagoner, Robin Gaines Lanzi, Vikas Gupta and 6 more

Abstract read
In one paragraph

Article in Journal of primary care & community health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Lynn T MatthewsUniversity of Alabama at Birmingham, USA.ORCID 0000-0001-6167-6328
Madeline C PrattUniversity of Alabama at Birmingham, USA.ORCID 0000-0003-2255-0401
Oluwaseyi O IsehunwaUniversity of Alabama at Birmingham, USA.
Lillian M KlasenUniversity of Alabama at Birmingham, USA.
Samantha V HillEmory University, Atlanta, GA, USA.
Tina SimpsonTulane University, New Orleans, LA, USA.
Brook A HubnerUniversity of Alabama at Birmingham, USA.ORCID 0000-0001-5951-8363
Nicholas Van WagonerUniversity of Alabama at Birmingham, USA.ORCID 0000-0001-5424-5271
Robin Gaines LanziUniversity of Alabama at Birmingham, USA.ORCID 0000-0002-5013-4141
Vikas GuptaMontgomery Family Medicine Residency Program, AL, USA.
Trupti NadkarMontgomery Family Medicine Residency Program, AL, USA.ORCID 0009-0005-3716-8311
Shivani MalhotraUniversity of Alabama at Birmingham - Huntsville Medical, USA.
Douglas S KrakowerHarvard Medical School, Boston, MA, USA.
Tara E WoodUniversity of Alabama at Birmingham, USA.
Dustin M LongWake Forest University, Winston-Salem, NC, USA.ORCID 0000-0002-5423-4481
Latesha E ElopreUniversity of Alabama at Birmingham, USA.

Funding

Mentoring in patient-oriented research on HIV prevention in the U.S. and Global SouthK24AI184259 · NIAID · YALE UNIVERSITY · PI Lynn T Matthews · 2025 to 2026
$361k
ETIOLOGICAL VARIATIONS IN DISRUPTIVE BEHAVIOR DISORDERSF31MH012804 · NIMH · UNIVERSITY OF DENVER · PI FRIEDMAN, MELANIE C · 2000 to 2001
$67k
NIAID NIH HHS K24 AI184259NIMH NIH HHS F31 MH012804
6 · The paper itself

Abstract

backgroundAdolescent girls and young women (AGYW) in the U.S. Southeast are disproportionately affected by HIV. We developed and piloted PrEP-Pro, an intervention to support family medicine residents to prescribe HIV pre-exposure prophylaxis (PrEP), with a focus on AGYW. We pilot-tested the intervention, evaluating feasibility, acceptability, and appropriateness.

methodsUsing intervention mapping, we developed sexual history training, PrEP curricula, and a PrEP champion program. For the 6-month pilot test, we trained PrEP champions who trained and supported residents at their sites. Participating physicians completed enrollment and exit questionnaires capturing PrEP provision experiences, attitudes/skills/barriers to completing a sexual history, and PrEP knowledge/attitudes/beliefs. Exit questionnaires assessed PrEP-Pro acceptability, feasibility, and appropriateness. We compared enrollment and exit scores on sexual history assessment, PrEP knowledge, and provider behaviors.

resultsAmong 46 participants (median age = 29 years), 57% were men, 59% were White, 15% were Asian, 11% were Latinx, and 7% were Black. Among 32 (70%) participants completing both enrollment and exit questionnaires, we observed significant increases in sexual history skills, PrEP knowledge, and PrEP attitudes, and non-significant increases in the proportion reporting routine sexual history assessment and HIV testing. On a 5-point scale, feasibility (mean 4.28 (SD = 0.42), acceptability (4.31 (0.53)), and appropriateness (4.25 (0.46)) scores were high with respect to the PrEP-Pro intervention.

conclusionThis multi-component intervention was feasible, acceptable, and appropriate for family medicine residents in the pilot. Pre- and post-evaluation suggest participation in the intervention increased PrEP knowledge and improved sexual history-taking. These findings suggest that the intervention could successfully enhance provider self-efficacy in delivering sexual health care.

Indexed as

Family PracticeHIV InfectionsPre-Exposure ProphylaxisAdolescentAdultFemaleHealth Knowledge, Attitudes, PracticeHumansInternship and ResidencyMalePilot ProjectsSurveys and QuestionnairesYoung Adultadolescent healthHIVPrEPreproductive healthsexual healthSoutheast U.S.

Identifiers

PMID41324173
PMCPMC12669483

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.