Observational studyActa paediatrica (Oslo, Norway : 1992)2026
Increased Incidence of Type 1 Diabetes and Co-Existing Thyroid Autoimmunity During the COVID-19 Pandemic in Sweden.
Observational study in Acta paediatrica (Oslo, Norway : 1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Endocrine complications of COVID-19: diabetes, musculoskeletal, thyroid, pituitary, adrenal, and gonadal disorders.Journal of the Endocrine Society · 2026Review
- SARS-CoV-2 infection and COVID-19 vaccination and the risk for new-onset type 1 diabetes: a register-based population study in Sweden.Diabetologia · 2026Article
- The silent epidemic within the pandemic: pathophysiology and prediction of post-COVID-19 diabetes.Journal of translational medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
aimWe aimed to investigate if the incidence of type 1 diabetes increased in children during the SARS-CoV-2 pandemic and whether SARS-CoV-2 antibodies were more frequently present at diagnosis compared with healthy individuals. We also examined whether clinical characteristics and coexisting autoimmunity differed between SARS-CoV-2 antibody positive and negative individuals.
methodsThis retrospective, longitudinal observational study included children aged 0-17 years diagnosed with type 1 diabetes between 01 January 2018 and 31 December 2023 at Skåne University Hospital, Sweden. Blood samples were analysed for SARS-CoV-2 antibodies and islet autoantibodies and compared to analyses of healthy children from the same period. Clinical characteristics and thyroid autoimmunity at onset were collected from medical records.
resultsThe incidence of type 1 diabetes increased from 40/100.000 (pre-pandemic) to 53/100.000 (pandemic). Children diagnosed with type 1 diabetes more likely tested positive for SARS-CoV-2 nucleocapsid protein (NCP) antibodies compared to healthy children. The SARS-CoV-2-NCP positive group had a higher prevalence of thyroid autoimmunity compared to the SARS-CoV-2-NCP negative group.
conclusionThe incidence of type 1 diabetes increased during the SARS-CoV-2 pandemic, with a possible connection to COVID-19. Interestingly, children positive for SARS-CoV-2 antibodies at type 1 diabetes diagnosis had a higher likelihood of thyroid autoimmunity compared to children negative for SARS-CoV-2 antibodies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.