ReviewCurrent research in microbial sciences2025
A thorough insight into the life cycle of the Epstein-Barr virus. From the molecular to the organismal level.
Review in Current research in microbial sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Viruses are known to be a specific form of life capable of reproduction exclusively by subjugating cellular life forms, where they have reached impressive heights. Especially complex and therefore interesting are pathogens, which have chosen maximum adaptation to the host as their survival strategy. In this review, we attempt to comprehensively describe the life cycle of one of the most adapted human pathogens - the Epstein-Barr virus (EBV). Despite significant efforts to study the biology of this virus, forming a complete picture of its life cycle based on scattered reports is currently a difficult task. This makes the understanding of EBV fragmentary and often insufficient for an analysis of the experimental data. Based on the currently available non-contradictory data, we consider most stages of the EBV life cycle and interpret them in the context of its survival strategy. We emphasize the features of EBV tropism to different types of susceptible cells, and describe the stages of entry and initial establishment of infection, the transition to latency and its various stages in the context of gentle subjugation of the host metabolism, the use of the host immune system for maximum disguise, the mechanisms of reactivation, and the lytic cycle and the associated remodeling of cell membranes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.