ArticleJournal of the Society for Cardiovascular Angiography & Interventions2025
Angiography-Derived Versus Coronary Guidewire-Derived Index of Microcirculatory Resistance in Patients With Ischemia With Nonobstructive Coronary Arteries.
Article in Journal of the Society for Cardiovascular Angiography & Interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Coronary function testing (CFT) during invasive coronary angiography is guideline-recommended to identify coronary microvascular dysfunction (CMD) in patients with ischemia with nonobstructive coronary arteries (INOCA). Wire-free, angiography-derived index of microcirculatory resistance (IMR Methods: This single-center observational study prospectively enrolled adults aged >18 years who were referred for clinically indicated invasive coronary angiography for the evaluation of chest discomfort or an anginal equivalent and had no coronary artery lesions with ≥50% stenosis. Participants underwent invasive CFT using bolus thermodilution techniques to determine IMR and coronary flow reserve (CFR) in the left anterior descending artery. IMR Results: Among 122 enrolled participants with INOCA (median age 62 years, 77% women), the median IMR in the left anterior descending artery was 20 (13-27), CFR was 3.95 (2.5-4.7), and 54 participants (44%) had CMD. IMR Conclusions: In patients with INOCA, correlations between IMR
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