Evidence map›Paper›PMID 41324025›Full record

ArticleClinical neurophysiology practice2025

Switch-Off response to mid-cingulate cortex stimulation: a video case report.

Paola Vassallo, Olivia Poole, Xiaodong Guan, Davide Giampiccolo, Eduardo Marques, Umesh Vivekananda, John S Duncan, Beate Diehl

Abstract readCase Reports
In one paragraph

Article in Clinical neurophysiology practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paola VassalloDepartment of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.
Olivia PooleDepartment of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.
Xiaodong GuanDepartment of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.
Davide GiampiccoloDepartment of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.
Eduardo MarquesDepartment of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.
Umesh VivekanandaDepartment of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.
John S DuncanDepartment of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.
Beate DiehlDepartment of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Electrical cortical stimulation (ECS) is commonly used during invasive presurgical evaluation of drug-resistant focal epilepsy for functional mapping and delineation of the epileptogenic zone. Case presentation: A 31-year-old woman underwent stereo-EEG evaluation for presurgical assessment of drug-resistant focal epilepsy, likely left frontal or multifocal. During 50 Hz ECS of the right mid-cingulate cortex, a reproducible behavioural response was observed, characterised by left ear popping, head drop, eye closure, and speech/motor arrest, without loss of awareness. This semiology differed from her habitual seizures, and the region was not considered part of the presumed epileptogenic zone. Conclusion: This case represents a rare video-documentation of stimulation-induced complex motor and behavioural response localised to the mid-cingulate cortex and supports mid-cingulate's role as connection hub for volitional control and sensorimotor integration.

Indexed as

Cingulate cortexElectrical cortical stimulationSEEG

Identifiers

PMID41324025
PMCPMC12661145

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.