Reviewnpj biomedical innovations2025
Stem cell-based therapies for treatment of abdominal aortic aneurysm: development, application, and future potential.
Seleem Badawy, Shivesh Anand, Ande X Marini, Joscha Mulorz, Philip S Tsao, Ngan F Huang
Abstract readReview
In one paragraphReview in npj biomedical innovations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
6 authors.
Seleem BadawyDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA USA.
Shivesh AnandDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA USA.
Ande X MariniDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA USA.
Joscha MulorzCenter for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto, Health Care System, Palo Alto, CA USA.
Philip S TsaoCenter for Tissue Regeneration, Repair and Restoration, Veterans Affairs Palo Alto, Health Care System, Palo Alto, CA USA.
Ngan F HuangDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA USA.
Funding
Stanford Vision Training ProgramT32EY027816 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2018 to 2026
$2.0MDevelopment of a Bioengineered Therapeutic Device for the Prevention of LymphedemaR01CA285372 · NCI · PALO ALTO VETERANS INSTIT FOR RESEARCH · PI Ngan F. Huang, Michael Vitoldovich Paukshto · 2024 to 2026
$1.6MBiomaterials for delivery and maintenance of tip endothelial cellsR21HL172096 · NHLBI · UNIVERSITY OF CALIFORNIA, MERCED · PI HUANG, NGAN F., MCCLOSKEY, KARA E · 2024 to 2025
$643kEnhance Cell Therapies for Peripheral Arterial Disease Using Human-Compatible Protease-Based ControlsR21HL177570 · NHLBI · STANFORD UNIVERSITY · PI GAO, XIAOJING J, HUANG, NGAN F. · 2025 to 2025
$410kNovel Highly Regenerative and Scalable Progenitor Cell Exosomes for Treating Peripheral Artery DiseaseR41HL170875 · NHLBI · SERINA THERAPEUTICS, INC. · PI HUANG, NGAN F., LEE, JI EUN · 2023 to 2023
$341k2024-2026 Biomedical Engineering Society (BMES) Cellular and Molecular Bioengineering (CMBE) ConferenceR13EB035466 · NIBIB · BIOMEDICAL ENGINEERING SOCIETY · PI Evangelia Bellas · 2024 to 2026
$33kBLRD VA I01 BX004259BLRD VA I01 BX006882BLRD VA IK6 BX006309NCI NIH HHS R01 CA285372NEI NIH HHS T32 EY027816NHLBI NIH HHS R21 HL172096NHLBI NIH HHS R21 HL177570NHLBI NIH HHS R41 HL170875NIBIB NIH HHS R13 EB035466RRD VA I21 RX004898
6 · The paper itselfAbstract
Abdominal aortic aneurysms (AAA), with approximately 200,000 new diagnoses each year, represent a prevalent clinical concern. Current treatment includes monitoring and surgical procedures once the aneurysm reaches a certain size. However, the lack of effective, timely therapies leads to a high mortality rate due to rupture. With recent advancements and innovations in biomedical science, stem cell therapy has moved closer to widespread clinical use, with the field experiencing rapid growth since its inception in the late 20
Indexed as
Cardiovascular biologyMesenchymal stem cellsPluripotent stem cells
Identifiers
PMID41323882
PMCPMC12657235
What OpenQuestion holds
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LicenceCC BY
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