Evidence map›Paper›PMID 41323877›Full record

ArticleThe Lancet regional health. Europe2026

Outcomes of adults with community-acquired bacterial meningitis in the Netherlands: a prospective nationwide cohort study.

Evelien H G M Drost, Eva N Schepers, Nora Chekrouni, Thijs M van Soest, Diederik L H Koelman, Merijn W Bijlsma, Matthijs C Brouwer, Diederik van de Beek

Abstract read
In one paragraph

Article in The Lancet regional health. Europe, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Suspected acute bacterial meningitis in adult emergency department: use of imaging before lumbar puncture and association with time to antibiotic initiation - a multicentre retrospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Evelien H G M DrostDepartment of Neurology, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands.
Eva N SchepersDepartment of Neurology, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands.
Nora ChekrouniDepartment of Neurology, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands.
Thijs M van SoestDepartment of Neurology, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands.
Diederik L H KoelmanDepartment of Neurology, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands.
Merijn W BijlsmaDepartment of Neurology, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands.
Matthijs C BrouwerDepartment of Neurology, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands.
Diederik van de BeekDepartment of Neurology, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bacterial meningitis is associated with high rates of unfavourable outcome. We conducted a nationwide prospective study in the Netherlands to evaluate outcome in adults with bacterial meningitis, focusing on pathogen-specific differences, risk factors for unfavourable outcomes, and neurological sequelae. Methods: Adult patients with community-acquired bacterial meningitis confirmed by lumbar puncture were identified through the database of the Netherlands Reference Laboratory for Bacterial Meningitis and prospectively included. Neurological examinations were performed on admission and discharge by the treating physician, and outcome was assessed using the Glasgow Outcome Scale, with scores of 1-4 classified as unfavourable. Logistic regression was used to evaluate the association between potential predictors and outcome. Findings: Between January 1, 2006 and January 1, 2024, 2974 patients were included. Interpretation: Mortality and morbidity from bacterial meningitis remain high, especially in Funding: Netherlands Organization for Health Research and Development (ZonMW).

Indexed as

Bacterial meningitisDexamethasoneHaemophilus influenzaeListeria monocytogenesNeisseria meningitidisNeurological sequelaeStreptococcus pneumoniaeStreptococcus pyogenes

Identifiers

PMID41323877
PMCPMC12662076

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.