Evidence map›Paper›PMID 41323702›Full record

ArticleRSC advances2025

From amides to thioamides: understanding enhanced anion binding in acyclic receptors.

Nasim Akhtar, Siebe Lekanne Deprez, Senuri G Jayawardana, Macallister Davis, Célia Fonseca Guerra, Víctor García-López

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nasim AkhtarDepartment of Chemistry, Louisiana State University Baton Rouge LA 70803 USA vglopez@lsu.edu.ORCID https://orcid.org/0009-0007-3442-3502
Siebe Lekanne DeprezDepartment of Chemistry and Pharmaceutical Sciences, Amsterdam Institute for Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam De Boelelaan 1108 1081 HZ Amsterdam The Netherlands c.fonsecaguerra@vu.nl.ORCID https://orcid.org/0000-0001-8040-9030
Senuri G JayawardanaDepartment of Chemistry, Louisiana State University Baton Rouge LA 70803 USA vglopez@lsu.edu.
Macallister DavisDepartment of Chemistry, Louisiana State University Baton Rouge LA 70803 USA vglopez@lsu.edu.
Célia Fonseca GuerraDepartment of Chemistry and Pharmaceutical Sciences, Amsterdam Institute for Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam De Boelelaan 1108 1081 HZ Amsterdam The Netherlands c.fonsecaguerra@vu.nl.ORCID https://orcid.org/0000-0002-2973-5321
Víctor García-LópezDepartment of Chemistry, Louisiana State University Baton Rouge LA 70803 USA vglopez@lsu.edu.ORCID https://orcid.org/0000-0003-2915-4591

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We synthesized acyclic amide and thioamide-based receptors and evaluated their anion binding efficacy experimentally and computationally. Our study shows the receptors adopt favorable conformations upon chloride binding and confirms that the stronger NH donor ability of thioamides arises from sulfur's larger size relative to oxygen. Moreover, the anion size dictates selectivity.

Identifiers

PMID41323702
PMCPMC12661136

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.