Evidence map›Paper›PMID 41323653›Full record

ArticleFrontiers in aging neuroscience2025

Self-reported hopefulness and cognitive function: the moderating effect of physical activity in older adults without cognitive impairment.

Boung Chul Lee, Young Min Choe, Ji-Hyun Kim, Hye Ji Choi, Guk-Hee Suh, Shin Gyeom Kim, Hyun Soo Kim, Jaeuk Hwang, Dahyun Yi, Jee Wook Kim

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Article in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Boung Chul LeeDepartment of Neuropsychiatry, Hallym University Hangang Sacred Heart Hospital, Seoul, Republic of Korea.
Young Min ChoeDepartment of Psychiatry, Hallym University College of Medicine, Chuncheon, Gangwon, Republic of Korea.
Ji-Hyun KimDepartment of Neuropsychiatry, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Gyeonggi, Republic of Korea.
Hye Ji ChoiDepartment of Neuropsychiatry, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Gyeonggi, Republic of Korea.
Guk-Hee SuhDepartment of Psychiatry, Hallym University College of Medicine, Chuncheon, Gangwon, Republic of Korea.
Shin Gyeom KimDepartment of Neuropsychiatry, Soonchunhyang University Bucheon Hospital, Bucheon, Republic of Korea.
Hyun Soo KimDepartment of Laboratory Medicine, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Gyeonggi, Republic of Korea.
Jaeuk HwangDepartment of Psychiatry, Soonchunhyang University Hospital, Seoul, Republic of Korea.
Dahyun YiInstitute of Human Behavioral Medicine, Medical Research Center Seoul National University, Seoul, Republic of Korea.
Jee Wook KimDepartment of Psychiatry, Hallym University College of Medicine, Chuncheon, Gangwon, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: With dementia cases rising globally, identifying modifiable psychological factors that support cognitive resilience is crucial. Hopefulness, an optimistic emotional state, may serve as a protective factor against cognitive decline. However, its role in cognitively normal (CN) individuals remains underexplored. We aim to investigate the association between self-reported hopefulness and overall cognitive function in CN older adults and to examine the moderating effect of physical activity on this relationship. Methods: A total of 152 CN adults aged 65-90 years were included in the General Lifestyle and Alzheimer's Disease (AD) study. Hopefulness was assessed by the Geriatric Depression Scale item "Are you hopeful about the future?," with "Yes" and "No" responses defining the hopefulness and non-hopefulness groups. Cognitive function was measured using the total score (TS) of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) neuropsychological battery. Physical activity was evaluated using the Physical Activity Scale for the Elderly. Results: Participants in the hopefulness group showed significantly higher TS scores compared to the non-hopefulness group (B = 5.009, Conclusion: Self-reported hopefulness, defined as optimism about the future, is positively associated with cognitive function in CN older adults, particularly among those with high-to-moderate physical activity levels. Interventions promoting both emotional well-being and physical activity may offer synergistic benefits for cognitive health.

Indexed as

Alzheimer’s diseasecognitioncognitively normalhopefulnessphysical activity

Identifiers

PMID41323653
PMCPMC12660227

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.