Trial reportFrontiers in public health2025
Effects of high-intensity interval training combined with dietary intervention on body composition, cardiovascular function, endothelial cell function and blood lipid indexes in children with obesity: a randomized controlled trial.
Trial report in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Exercise training modalities for cardiorespiratory fitness and blood pressure in children and adolescents with obesity: a systematic review and network meta-analysis.Frontiers in public health · 2026Pooled it
- Effect of lifestyle interventions on pediatric obesity: a lifestyle medicine systematic review.Clinical and experimental pediatrics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To investigate the combined effects of moderate-intensity continuous training(MICT), high-intensity interval training (HIIT) and HIIT combined with dietary intervention on body composition, cardiovascular function, and endothelial cell function (as assessed by biomarkers including endothelin-1 and nitric oxide) in overweight children aged 9-12 years with a BMI ≥ 23 kg/m Methods: A total of 90 overweight children were randomly assigned into three groups with a 1:1 gender ratio: moderate-intensity continuous training group (MICT, Results: After the intervention, all three groups showed significant reductions in body mass index and fat mass. Intergroup comparisons revealed that the Joint Intervention group demonstrated superior improvements in body composition indicators. Both HIIT groups showed greater reductions in body fat percentage compared to the MICT group ( Conclusion: The combination of high-intensity interval training and dietary intervention promotes fat reduction, enhances antioxidant capacity, and improves cardiorespiratory function in overweight children. This integrated approach effectively improves body mass index, cardiovascular function, and endothelial cell function. The remarkable efficacy of this combined intervention suggests its potential value for clinical application and integration into school-based programs aimed at addressing childhood obesity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.