SynthesisFrontiers in public health2025
The bidirectional association between depression and sarcopenia: a systematic review and meta-analysis.
Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Sarcopenia and depression: a strong association in older adults with type 2 diabetes in Vietnam.BMC geriatrics · 2026Article
- Unseen burden: Prevalence and determinants of possible sarcopenia in Indonesian older adults - a secondary data analysis.Belitung nursing journal · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
Background: Sarcopenia, a geriatric syndrome characterized by progressive loss of muscle mass, strength, and physical performance, elevates risks of functional decline and mortality. This study aims to investigate the co-occurrence patterns between depression and sarcopenia and characterize their epidemiological linkages. Methods: We systematically searched PubMed, Embase, Scopus, and Web of Science for studies examining depression and sarcopenia (published by July 12, 2024). Our review encompasses literature on sarcopenia prevalence, its co-occurrence with depression, and the odds ratio (OR) between these conditions. We performed statistical analyses using R. Results: Analysis of 36 studies demonstrated significantly higher pooled depression prevalence among sarcopenic individuals (0.24; 95% CI: 0.18-0.30; Conclusion: Sarcopenia is significantly associated with higher depression prevalence and increased depression likelihood. While sarcopenia prevalence is elevated in depression populations, their bidirectional association requires further investigation. Future research should focus on elucidating underlying mechanisms. Systematic review registration: This review was registered with PROSPERO (number CRD42024572944).
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