Evidence map›Paper›PMID 41323477›Full record

ArticleVeterinary and animal science2025

A bromoform based Investigational Veterinary Product fed twice daily to lactating dairy cows had no adverse effects on eating, rumination, or locomotion behaviours.

R Tognelli, P S Alvarez-Hess, A S Ó Neachtain, S Chandra, S R O Williams, S Jacques, S E Denman, R J Eckard, J L Jacobs

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary and animal science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

R TognelliAgriculture Victoria Research, Department of Energy, Environment and Climate Action Ellinbank, Victoria, 3821, Australia.
P S Alvarez-HessSchool of Agriculture, Food and Ecosystem Sciences, Faculty of Science, The University of Melbourne, Victoria, 3010, Australia.
A S Ó NeachtainAgriculture Victoria Research, Department of Energy, Environment and Climate Action Ellinbank, Victoria, 3821, Australia.
S ChandraAgriculture Victoria Research, Department of Energy, Environment and Climate Action, Tatura, Victoria, 3616, Australia.
S R O WilliamsAgriculture Victoria Research, Department of Energy, Environment and Climate Action Ellinbank, Victoria, 3821, Australia.
S JacquesRumin8 Pty Ltd, Suite 1, Level 2, 66 Kings Park Road, West Perth 6005, WA, Australia.
S E DenmanCSIRO, Agriculture Flagship, Queensland Bioscience Precinct, St. Lucia, QLD, Australia.
R J EckardSchool of Agriculture, Food and Ecosystem Sciences, Faculty of Science, The University of Melbourne, Victoria, 3010, Australia.
J L JacobsAgriculture Victoria Research, Department of Energy, Environment and Climate Action Ellinbank, Victoria, 3821, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An Investigational Veterinary Product (IVP) containing synthetic bromoform has emerged as a promising technology for reducing livestock enteric methane emissions. However, the effects of feeding the bromoform-based IVP on eating, rumination and locomotion behaviour (critical animal welfare indicators) remain unclear. This study assessed the response of supplementing twice daily an IVP at two bromoform inclusion rates to lactating dairy cows at milking on i) eating and rumination behaviour; and ii) locomotion behaviour. Thirty multiparous, Holstein-Friesian cows (214 ± 15.2 days in milk) were allocated to one of three treatments; CON (0 mg bromoform/cow per day), LowBR (227 mg bromoform/cow per day) and HighBR (455 mg bromoform/cow per day). The IVP was mixed with 3.1 kg dry matter of grain and offered during each milking. The basal diet consisted of vetch hay offered

Indexed as

Animal welfareFeed additivesMethane mitigationRuminants

Identifiers

PMID41323477
PMCPMC12664077

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.