Evidence map›Paper›PMID 41323460›Full record

ArticleThe Pan African medical journal2025

IVIg-induced false positive hepatitis B serology in a patient with Guillain-Barré syndrome: a case report.

Yasmine Bendimrad, Lina Seffar, Malak Snoussi, Jalila El Bakkouri

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The Pan African medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yasmine BendimradFaculty of Pharmacy, Mohammed VI University of Sciences and Health, Casablanca, Morocco.
Lina SeffarLaboratory Medicine, Cheikh Khalifa International University Hospital, Mohammed VI University of Sciences and Health, Casablanca, Morocco.
Malak SnoussiLaboratory Medicine, Cheikh Khalifa International University Hospital, Mohammed VI University of Sciences and Health, Casablanca, Morocco.
Jalila El BakkouriLaboratory Medicine, Cheikh Khalifa International University Hospital, Mohammed VI University of Sciences and Health, Casablanca, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 63-year-old Moroccan male with Guillain-Barré syndrome (GBS) who, following treatment with intravenous immunoglobulin (IVIg), developed false-positive anti-HBs and anti-HBc antibodies. This occurred despite negative pre-treatment serology and led to diagnostic confusion. A negative hepatitis B viral DNA PCR confirmed the absence of an active infection. This case highlights a crucial takeaway lesson for clinicians: IVIg can interfere with viral serological assays, and this possibility should be considered to avoid misinterpretation and unnecessary interventions.

Indexed as

Guillain-Barre SyndromeHepatitis BHepatitis B AntibodiesImmunoglobulins, IntravenousDNA, ViralFalse Positive ReactionsHepatitis B Core AntigensHepatitis B Surface AntigensHepatitis B virusHumansMaleMiddle AgedPolymerase Chain ReactionDNA, ViralHepatitis B AntibodiesHepatitis B Core AntigensHepatitis B Surface AntigensImmunoglobulins, Intravenouscase reportfalse positiveGuillain-Barré syndromeIntravenous immunoglobulinserological interference

Identifiers

PMID41323460
PMCPMC12661974

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.