Evidence map›Paper›PMID 41323287›Full record

ArticleiScience2025

Resolving oligomeric states of photoactivatable proteins in living cells via photon counting histogram analysis.

Tyler Camp, Zixiao Li, Yushan Li, Teak-Jung Oh, Kai Zhang

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tyler CampDepartment of Biochemistry, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Zixiao LiDepartment of Biochemistry, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Yushan LiDepartment of Biochemistry, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Teak-Jung OhDepartment of Biochemistry, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Kai ZhangDepartment of Biochemistry, University of Illinois Urbana-Champaign, Urbana, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oligomerization of photoactivatable proteins underlies many optogenetic strategies, yet their assembly states remain difficult to quantify in living cells. Here, we applied photon counting histogram analysis to directly measure the oligomerization of widely used optogenetic modules,

Indexed as

molecular interactionproteinstructural biology

Identifiers

PMID41323287
PMCPMC12661439

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.