Evidence map›Paper›PMID 41323221›Full record

ArticleFrontiers in neurology2025

Study on the relationship between insomnia disorder, PET/CT, and gut microbiota in patients with Alzheimer's disease.

Jian Kang, Jianwen Chen, Peixue Li, Shiqi Zhao, Fangfang Jing, Jinghui Xie, Chunbo Dong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jian Kang *Department of Neurology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Jianwen Chen *Department of Neurology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Peixue LiDepartment of Neurology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Shiqi ZhaoDepartment of Neurology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Fangfang JingDepartment of Neurology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Jinghui XieDepartment of Nuclear Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Chunbo DongDepartment of Neurology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Previous studies on Alzheimer's disease (AD) have focused on the relationships between brain pathology and gut microbiota, brain pathology and sleep, and sleep and gut microbiota, but no study has explored the relationship between these three factors. Therefore, we integrated these three factors into a unified framework and aimed to provide a reference for treating insomnia disorders (ID) in patients with AD. Patients/methods: The 65 patients diagnosed with AD were categorized into ID group ( Results: Data with significant differences ( Conclusion: In AD patients with ID, there may be both a direct and an indirect association between

Indexed as

Alzheimer’s diseasebrain pathologygut microbiotainsomnia disorderpositron emission tomography

Identifiers

PMID41323221
PMCPMC12658357

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.