Evidence map›Paper›PMID 41323144›Full record

ArticleTransboundary and emerging diseases2025

Severe Diarrhea Outbreaks in Newborn Piglets in China Associated With Porcine Rotavirus B.

Mingkai Sun, Tianzeng Li, Wugang Liu, Zhixing Guo, Zunbao Wang, Jianfeng Jiang, Qingxian Li, Biao He, Yidi Guo, Wenjie Gong

Abstract read
In one paragraph

Article in Transboundary and emerging diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mingkai SunState Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.ORCID https://orcid.org/0009-0002-8848-9279
Tianzeng LiTECON Biopharmaceutical Co. Ltd., Urumqi, China.ORCID https://orcid.org/0009-0002-1249-1946
Wugang LiuTECON Biopharmaceutical Co. Ltd., Urumqi, China.ORCID https://orcid.org/0009-0002-8391-2373
Zhixing GuoZhejiang Meibaolong Biotechnology Co. Ltd., Hangzhou, China.ORCID https://orcid.org/0009-0005-1091-5962
Zunbao WangTECON Biopharmaceutical Co. Ltd., Urumqi, China.ORCID https://orcid.org/0009-0009-5707-1540
Jianfeng JiangState Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.ORCID https://orcid.org/0000-0002-7625-0570
Qingxian LiState Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.ORCID https://orcid.org/0000-0003-2544-0726
Biao HeState Key Laboratory of Pathogen and Biosecurity, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, China.ORCID https://orcid.org/0000-0001-7587-152X
Yidi GuoState Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.ORCID https://orcid.org/0000-0003-3187-896X
Wenjie GongState Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.ORCID https://orcid.org/0009-0008-2026-5977

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rotavirus B (RVB) is among the enteric pathogens that can cause gastroenteritis in humans and various animals. However, severe diarrhea in newborn piglets has rarely been reported to be linked to porcine RVB (PoRVB). From 2023 to 2024, outbreaks of newborn piglet diarrhea with 20%-50% morbidity and 4%-10% mortality occurred in three herds situated in Anhui, Liaoning, and Jilin provinces of China. Notably, all samples from these herds tested negative for porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), PoRVA and transmissible gastroenteritis virus (TGEV). To identify the causative pathogens of the severe diarrhea in newborn piglets, high-throughput sequencing (HTS) was performed on pooled and individual samples collected from each farm. The results revealed that there were 783,546-1,237,231 mammalian virus reads per pooled sample, with PoRVB being the overwhelmingly dominant virus. A high prevalence of PoRVB (83.3%-100%) was detected in all the affected farms, indicating the association between PoRVB strains and the outbreak of severe piglet diarrhea in the sampled farms. Analysis of

Indexed as

DiarrheaDisease OutbreaksRotavirusRotavirus InfectionsSwine DiseasesAnimalsAnimals, NewbornChinaPhylogenySwinegenotypingphylogenetic analysispiglet diarrheaPoRVB

Identifiers

PMID41323144
PMCPMC12662673

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.