ArticleFood & nutrition research2025
Association between Health Eating Index-2015 and prostate-specific antigen levels: a cross-sectional study of NHANES 2001-2004.
Article in Food & nutrition research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: Prostate cancer is the most common carcinoma among men worldwide. To elaborate the effect of dietary quality on prostate-specific antigen (PSA), we investigated the association between Health Eating Index-2015 (HEI-2015) and PSA concentration from National Health and Nutrition Examination Survey. Methods: This cross-sectional analysis of men aged 40 years and older was enrolled from the year 2001-2004. Weighted multivariable logistic and linear regression models were employed to evaluate the association between the HEI-2015 and PSA level. Results: A total of 1,467 males were enrolled in the study. The results demonstrated that a higher HEI-2015 score was associated with a lower PSA level in the fully-adjusted model (β = -0.388, 95% Confidence interval (CI) = -0.746 to -0.030, Conclusion: Our findings indicate that a higher HEI-2015 score is associated with a reduced risk of PSA among adult men aged 40-55 years in the United States. Furthermore, race, body mass index (BMI), and alcohol drinking may be modifiers of the relationship.
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