Evidence map›Paper›PMID 41323065›Full record

ArticleEcology and evolution2025

Experimentally Testing the Hypothesis That Hybrid Fitness Can Increase Evolutionarily: An Example in Spadefoot Toads.

Sedona Ryan, Patrick Kelly, Bryson Loflin, Karin S Pfennig

Abstract read
In one paragraph

Article in Ecology and evolution, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sedona RyanEnvironment, Ecology and Energy Program University of North Carolina at Chapel Hill Chapel Hill North Carolina USA.ORCID https://orcid.org/0009-0002-8453-9320
Patrick KellyDepartment of Biology University of North Carolina at Chapel Hill Chapel Hill North Carolina USA.ORCID https://orcid.org/0000-0002-5114-6849
Bryson LoflinDepartment of Biology University of North Carolina at Chapel Hill Chapel Hill North Carolina USA.ORCID https://orcid.org/0009-0002-3302-4167
Karin S PfennigEnvironment, Ecology and Energy Program University of North Carolina at Chapel Hill Chapel Hill North Carolina USA.ORCID https://orcid.org/0000-0002-0852-287X

Funding

Tri-Institutional Molecular Mycology and Pathogenesis Training ProgramT32AI052080 · NIAID · DUKE UNIVERSITY · PI ANDREW ALSPAUGH, JOSEPH HEITMAN · 2003 to 2026
$8.7M
NIAID NIH HHS T32 AI052080
6 · The paper itself

Abstract

Hybrids often have reduced fitness because of genetic incompatibilities. If populations contain variation at loci involved in these genetic incompatibilities, then selection can disfavor alleles involved in incompatibilities, thereby reducing their frequency within the parent-lineages' gene pools in the hybridizing population. Such selection can concomitantly increase hybrid fitness in populations over evolutionary time. This hypothesis predicts that hybrid fitness should be higher in populations where species have hybridized for longer periods (or where hybridization is more frequent) versus in populations where species have hybridized for a shorter duration (or where hybridization is less frequent). We tested this prediction in spadefoot toads,

Indexed as

adaptive hybridizationBateson‐Dobzhansky‐Mullergenetic incompatibilitiesintrogressionreinforcementspeciation

Identifiers

PMID41323065
PMCPMC12659929

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.