Evidence map›Paper›PMID 41323055›Full record

ArticleCase reports in oncology

Excellent Response and Persistent Local Control of Metastatic Extraskeletal Myxoid Chondrosarcoma Repeatedly Treated with Surgical Excision or Stereotactic Radiotherapy Alone: A Case Report.

Giorgia Timon, Massimiliano Grassi, Celjeta Tominaj, Marianna Turazzi, Matteo Mascherini, Franco De Cian, Bruno Spina, Federico Zaottini, Federico Pistoia, Salvina Barra and 2 more

Abstract readCase Reports
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Giorgia TimonDepartment of Radiotherapy, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Massimiliano GrassiMedical Oncology Unit 1, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Celjeta TominajDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Marianna TurazziDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Matteo MascheriniSurgical Clinical Unit 1, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Franco De CianSurgical Clinical Unit 1, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Bruno SpinaS.C. Anatomia Patologica Ospedaliera, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Federico ZaottiniDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
Federico PistoiaRadiology Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Salvina BarraDepartment of Radiotherapy, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Danila ComandiniMedical Oncology Unit 1, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Liliana BelgioiaDepartment of Radiotherapy, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Extraskeletal myxoid chondrosarcoma (EMC) is an extremely rare mesenchymal tumor, accounting for less than 3% of soft tissue sarcomas. Even though metastatic rate after radical surgery in EMC can reach 50%, prolonged survival is common even in the presence of metastatic disease. Prospective studies evaluating the role of trabectedin, antiangiogenic agents, and immunotherapy are ongoing to assess the best systemic treatment. Case Presentation: We report the case of a young Sri Lankan woman who initially underwent neoadjuvant radiotherapy and surgery for a mass of the right thigh, then experienced local relapse, managed with chemotherapy and surgery again, and finally was diagnosed with distant progression. All metastatic sites of EMC were treated with either surgical excision or stereotactic ablative radiotherapy alone in three different occasions, showing complete or major response. Conclusion: This individualized approach enabled prolonged systemic therapy-free intervals with minimal toxicity, so could be considered in selected patients.

Indexed as

Extraskeletal myxoid chondrosarcomaMetastasisRadiotherapySoft tissue sarcomaStereotactic ablative radiotherapy

Identifiers

PMID41323055
PMCPMC12659415

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.