Evidence map›Paper›PMID 41323032›Full record

ArticleiLIVER2025

Recommendations for management of pregnancy complicated by Caroli disease: A case report and literature review.

Chen Liang, Li Bai, Wei Hou, Wen-Yan Song, Yun-Xia Zhu, Su-Jun Zheng

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in iLIVER, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chen LiangDepartment of Liver Disease, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China.
Li BaiDepartment of Liver Disease, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China.
Wei HouDepartment of Liver Disease, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China.
Wen-Yan SongDepartment of Medical Imaging, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China.
Yun-Xia ZhuDepartment of Obstetrics and Gynecology, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China.
Su-Jun ZhengDepartment of Liver Disease, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the clinical and genetic characteristics of a 28-year-old pregnant Chinese woman with Caroli disease (CD) and systematically reviewed the published literature on pregnancy complicated by CD. We reviewed our case and 8 patients with 9 pregnancies included in 6 reports. The main clinical characteristics of pregnancy complicated by CD are cholestasis, liver and renal insufficiency, portal hypertension, and cirrhosis. In severe cases, there may be an increased risk of disease progression during pregnancy. Management of pregnancy complicated by CD is primarily supportive. Antimicrobial therapy and prevention of cholestasis and portal hypertension are recommended. Patients may benefit from multidisciplinary care.

Indexed as

Caroli diseaseManagementMultidisciplinaryPregnancyRecommendation

Identifiers

PMID41323032
PMCPMC12664362

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.