ArticleInternational journal of nursing studies advances2025
Investigating whether routinely collected biomarkers improve the prediction of hospital-acquired pressure injury occurrence: A retrospective cohort study.
Article in International journal of nursing studies advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Predictors of Pressure Injury Development and Clinical Course in ICU Patients: A Retrospective Cohort Study.Healthcare (Basel, Switzerland) · 2026Article
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7 authors.
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Abstract
Background: Despite being largely preventable, hospital-acquired pressure injuries remain a significant challenge in healthcare, contributing to prolonged hospital stays, increased patient morbidity, and substantial healthcare costs. Commonly used risk assessment tools have limited predictive accuracy, and early detection of hospital acquired pressure injuries often depends on subjective visual skin assessments. Emerging evidence suggests routinely collected biomarkers may offer an objective and reliable approach to predicting hospital acquired pressure injuries risk. Objective: To explore how biomarkers improve hospital acquired pressure injuries prediction. Design: Retrospective cohort study. Setting: Acute NHS Trust in England, UK. Participants: 10,504 adult patients admitted to acute medical wards for at least 24 h in 2024. Methods: We considered the first hospital acquired pressure injuries and first record of other variables per hospital episode, measured at or soon after admission. Population characteristics of those who developed a hospital acquired pressure injuries or not were compared, overall and stratified by categories of length of stay (<6 days, ≥6 days), Braden, Malnutrition Universal Screening Tool and Mobility scores. Using multivariable logistic regression, we assessed the predictive value of the risk scores, adjusted for age and gender, and adding single biomarkers. Predictive performance was evaluated by discrimination and calibration. Analyses were exploratory. We used Stata v16 and R v4.4. Results: Median hospital stay for patients with hospital acquired pressure injuries ( Conclusions: This study provides insight into the potential role of biomarkers in enhancing hospital acquired pressure injuries risk prediction. Further research should investigate how using objective biomarkers, combined with risk scores, improves the prediction of hospital acquired pressure injuries.
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