ArticleCureus2025
Proximal Femoral Replacement for Prosthetic Hip Joint Infection.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRevision total hip arthroplasty is a surgical challenge when undertaken for hip prosthetic joint infection (PJI). When PJI occurs in the setting of severe proximal femoral bone loss, proximal femoral replacement (PFR) can serve as an effective salvage strategy, restoring function in prosthetic hips that cannot be reconstructed otherwise. MATERIALS AND
methodsThis retrospective series from a high-volume revision hip surgeon comprises 15 PFRs in 14 patients. Infection was the indication for surgery in all cases. Thirteen patients had confirmed PJI as per the 2018 Musculoskeletal Infection Society (MSIS) criteria. The primary outcome measure was the eradication of infection. Secondary outcome measures included peri- and postoperative complications, re-operation, mobility, and death. The mean follow-up was three years.
resultsInfection was eradicated in 13 cases (86.6%). Of the two cases with infection, one was asymptomatic for seven years before PJI became evident again. Complications included hip dislocation (three episodes in two patients). One patient underwent revision of the acetabular component due to infected loosening. All but one patient were ambulatory with walking aids. Both patients with persistent or recurrent infection subsequently died.
conclusionsPFR is an option for patients with PJI for whom standard revision hip arthroplasty would be unsuitable and excision surgery unacceptable. This study suggests promising results for the eradication of PJI using PFR as a salvage procedure in this particularly challenging cohort. LEVEL OF EVIDENCE: The study is classified as level IV evidence.
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