ArticleCureus2025
Temporal Changes in Microbial Etiology and Antibiotic Resistance Profiles of Osteoarticular Infections: An 11-Year Retrospective Analysis.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
backgroundOsteoarticular infections (OAIs) represent a serious clinical concern. Their management is complicated by shifting microbiological landscapes and rising antimicrobial resistance. This study aims to define the long-term trends in pathogen distribution and resistance patterns to guide empirical therapy. METHODOLOGY: An 11-year retrospective study (2013-2023) was conducted at Ibn Tofail University Hospital, affiliated with Mohammed VI University Hospital in Marrakech, Morocco. Bacterial isolates from deep osteoarticular samples were identified using standard methods. Antimicrobial susceptibility testing was performed according to the European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines. Statistical analysis was applied to determine significant trends over time.
resultsAmong 813 bacterial isolates, Gram-negative bacilli predominated (574/813, 70.6%), followed by Gram-positive cocci (239/813, 29.4%).
conclusionsThis retrospective longitudinal study identified
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