ArticleCureus2025
Trends and Disparities in Liver Cancer Incidence by Demographic Factors in the United States (1999-2020).
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
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Abstract
introductionAnalyzing liver cancer incidence is essential for identifying trends and determining risk factors, which, in turn, guide strategies for prevention and treatment. By focusing on high-risk populations, such analyses enhance health outcomes and cancer risk management. METHODOLOGY: A retrospective study was conducted using data from the Centers for Disease Control-Wide-ranging Online Data for Epidemiologic Research database (1999-2020) to evaluate liver cancer incidence trends in the United States (US) by age, gender, and race.
resultsDemographic variations of liver cancer in the US from 1999 to 2020 were determined. A state-wise distribution of crude rates per 100,000 and incidence across the US during the same period was established. Based on age, gender, and race, the fluctuating trends in liver cancer incidence from 1999 to 2020 were also investigated.
conclusionsThis study shows state-wise variations in liver cancer incidence; however, crude rates per 100,000 remain relatively consistent across states. Over 22 years, liver cancer rates have increased, with the highest incidence found in men, White individuals, and those aged 65-74. Incidence increased for individuals over 45, but by the end of two decades, rates for ages 45-54 decreased while remaining high for ages ≥55. A more prominent upward trajectory was observed in men compared to women and in Whites compared to other races, underscoring the need for targeted prevention and control strategies.
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