Evidence map›Paper›PMID 41322857›Full record

ArticleCureus2025

Clearance of 1-2 cm Renal Stones After Subjecting the Patients to Extracorporeal Shockwave Lithotripsy With and Without Double J Ureteral Stent.

Muhammad Khalid, Tariq Saleem Khan, Riaz Ahmad Khan, Ahmad Nawaz, Heraa Javed, Abdul Basit

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Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Muhammad KhalidDepartment of Accident and Emergency, Mian Rashid Hussain Shaheed Memorial Hospital, Pabbi, PAK.
Tariq Saleem KhanDepartment of Renal Transplantation, Institute of Kidney Diseases, Peshawar, PAK.
Riaz Ahmad KhanDepartment of Urology, Institute of Kidney Diseases, Peshawar, PAK.
Ahmad NawazDepartment of Urology, Institute of Kidney Diseases, Peshawar, PAK.
Heraa JavedDepartment of Radiology, MMC General Hospital, Peshawar, PAK.
Abdul BasitDepartment of Urology, Institute of Kidney Diseases, Peshawar, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRenal stones measuring 1-2 cm are a common urological problem frequently managed with extracorporeal shock wave lithotripsy (ESWL). However, the role of pre-procedural double J (DJ) stenting in improving stone clearance and minimizing complications remains controversial. Some studies suggest that stenting facilitates fragment passage and prevents steinstrasse, whereas others report increased patient discomfort and urinary symptoms.

objectiveThe objective of this study was to evaluate whether pre-ESWL DJ stenting improves stone clearance and reduces procedure-related complications in patients with 1-2 cm renal stones. HYPOTHESIS: Pre-procedural DJ stenting facilitates fragment clearance and lowers obstruction-related events without significantly increasing overall morbidity. MATERIALS AND

methodsThis was a prospective comparative study conducted in Pakistan from January 2022 to December 2024. A total of 230 patients with single renal stones (1-2 cm) were randomized into Group A (ESWL with pre-procedural DJ stenting) (n = 115) and Group B (ESWL without stenting) (n = 115). In Group A, 6 Fr polyurethane DJ stents were inserted under local or spinal anesthesia 24-48 hours before ESWL. Procedures were performed using lithotripters operated using standardized parameters (energy range 12-21 kV, up to 3,000 shocks per session, and 60-90 shocks per minute. A maximum of three sessions was performed, spaced 10-14 days apart. All patients received standardized analgesic (diclofenac sodium 75 mg IM) and prophylactic antibiotic (ciprofloxacin 500 mg twice daily for three days) regimens. Stents were removed after achieving clearance or within four weeks. Stone clearance was evaluated at two and four weeks post procedure using ultrasonography and non-contrast CT (NCCT) when needed. Complete clearance was defined as the absence of fragments >4 mm. Complications, including hematuria, renal colic, infection, steinstrasse, and stent-related symptoms, were recorded. Data were analyzed using chi-square and t-tests; multivariate logistic regression identified independent predictors of stone clearance.

resultsComplete clearance was achieved in 95 (82.6%) stented versus 78 (67.8%) non-stented patients (p = 0.012). Residual stones >4 mm occurred in five (4.3%) stented and 15 (13.0%) non-stented patients (p = 0.021). Hematuria was more frequent in the stent group (n=20; 17.4%) than in the non-stent group (n=10; 8.7%) (p = 0.048). Stent-related symptoms were reported in 28 (24.3%) patients. Steinstrasse occurred more commonly in the non-stent group (n=15; 13.0%) than the stent group (n=4; 3.5%) (p = 0.011), while renal colic was seen in 14 (12.2%) non-stented versus six (5.2%) stented patients (p = 0.049). Multivariate analysis confirmed DJ stenting as an independent predictor of clearance (OR = 2.14; 95%CI: 1.22-3.74; p = 0.007).

conclusionPre-ESWL DJ stenting is associated with higher stone clearance and fewer obstructive complications, such as steinstrasse and colic, but increases stent-related morbidity. Routine use in all patients is not justified; selective stenting should be considered for cases at higher risk of obstruction, including larger or impacted stones, solitary kidneys, or unfavorable anatomical configurations.

Indexed as

kidney calculilithotripsypostoperative complicationstreatment outcomeureteral stents

Identifiers

PMID41322857
PMCPMC12662765

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