ReviewCureus2025
Wrapping of the Gastroduodenal Artery Stump to Reduce Haemorrhage After Pancreaticoduodenectomy.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pancreaticoduodenectomy (PD) is a complex and high-risk surgical procedure associated with significant morbidity and mortality, particularly due to post-pancreatectomy haemorrhage (PPH). Wrapping the gastroduodenal artery stump (GDAS) intraoperatively has been proposed as a preventive measure, utilizing various materials such as the falciform ligament (FL), ligamentum teres hepatis (LTH), omentum, and polyglycolic acid (PGA) sheets. A comprehensive meta-analysis was conducted, including 10 studies involving 3,398 participants. Comparative studies were selected to evaluate the risk of PPH with GDAS wrapping versus control groups. Odds ratios (ORs) were used to assess efficacy. GDAS wrapping significantly reduced PPH incidence (OR = 0.23, 95% CI: 0.11-0.51), despite high heterogeneity among studies (I² = 64%). Subgroup analysis showed significant reductions with FL/LTH (OR = 0.20, p = 0.003) and PGA (OR = 0.18, p = 0.007) but not with omental (OR = 0.37, p = 0.07). The analysis of 30-day mortality did not reach significance (OR = 0.76, p = 0.44). GDAS wrapping may reduce PPH risk; however, further randomised studies are needed to confirm these findings and assess the superiority of specific wrapping techniques.
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