Evidence map›Paper›PMID 41322800›Full record

ReviewCureus2025

Recent Advances in the Diagnosis and Management of Pediatric Orthopedic Disorders: A Comprehensive Review.

Jitender Saini, Nischay Kaushik, Prerak Jain, Juvesh Kumar, Bhanupriya Singh

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jitender SainiDepartment of Orthopaedics, Dr. Baba Saheb Amedkar Medical College and Hospital, New Delhi, IND.
Nischay KaushikDepartment of Orthopaedics, Dr. Baba Saheb Amedkar Medical College and Hospital, New Delhi, IND.
Prerak JainDepartment of Orthopaedics, Dr. Baba Saheb Amedkar Medical College and Hospital, New Delhi, IND.
Juvesh KumarDepartment of Orthopaedics, Dr. Baba Saheb Amedkar Medical College and Hospital, New Delhi, IND.
Bhanupriya SinghDepartment of Radiodiagnosis, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric orthopedic disorders, spanning congenital, developmental, traumatic, infectious, and neoplastic conditions, are a major source of preventable disability worldwide. Despite notable advances over the past decade, progress in diagnostic precision, surgical innovation, and regenerative therapy development often remains compartmentalized within subspecialties, limiting the translation of innovations across the field. This review aims to summarize recent advances in pediatric orthopedic diagnosis and treatment, assess emerging technologies such as AI-assisted imaging and regenerative medicine, and highlight key challenges and evidence gaps to guide future practice. A structured literature search was conducted across major biomedical databases (PubMed, Scopus, and Web of Science) to identify studies focused on pediatric populations, emphasizing multicenter cohorts and randomized controlled trials (RCTs) when available. Key advances include radiation-sparing diagnostic tools such as artificial intelligence (AI)-assisted ultrasonography, low-dose cone-beam computed tomography (CBCT), and positron emission tomography/magnetic resonance imaging (PET/MRI); minimally invasive, growth-preserving interventions like guided growth, bioabsorbable fixation, and patient-specific three-dimensional (3D)-printed implants; and biologic augmentation approaches using platelet-rich plasma (PRP), mesenchymal stem cells (MSCs), and scaffold-based regeneration. While these innovations enhance diagnostic precision, reduce morbidity, and preserve skeletal potential, most are underpinned by Level II/III evidence and face barriers related to cost, access, and resource availability. By integrating cross-disciplinary progress and identifying transferable strategies, this review offers clinicians, researchers, and policymakers an actionable roadmap to align technological innovation with robust evidence generation and equitable delivery, ensuring sustainable improvements in musculoskeletal health for children globally.

Indexed as

artificial intelligencebiologic augmentationgrowth preservationpediatric orthopedicsregenerative medicine

Identifiers

PMID41322800
PMCPMC12659333

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.