ArticleCureus2025
Type II Gallbladder Perforation: A Management Conundrum or a Surgical Indecision?
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
backgroundGallbladder perforation (GBP) is a rare but serious complication of acute cholecystitis. Niemeier Type II, characterized by localized perforation with pericholecystic abscess, represents the most common subtype but lacks standardized management guidelines. This study aimed to evaluate clinical, radiologic, and comorbidity-related factors influencing treatment selection and outcomes in Type II GBP.
methodsWe retrospectively reviewed all radiologically diagnosed cases of GBP at a single university hospital between 2014 and 2022. Patients were classified according to Niemeier's system, with Type II cases subdivided by management approach: cholecystectomy, percutaneous cholecystostomy, interventional radiology (IR) drainage, or antibiotics alone. Data collected included demographics, Charlson Comorbidity Index (CCI), CT findings, length of stay (LOS), reintervention, readmissions, and mortality. Multivariate analysis identified predictors of management strategy and outcomes.
resultsNinety-one patients were identified, of whom Type II perforation accounted for 72 cases. Management strategies included cholecystectomy in 9 (13%) , cholecystostomy in 12 (17%), IR drainage in 17 (24%), and antibiotics alone in 33 (46%). One patient underwent combined IR drainage and cholecystostomy. Patients undergoing surgery had the lowest CCI, while conservative strategies were more common among older patients with a higher comorbidity burden. Gallbladder distension predicted cholecystostomy, while loculated collections were associated with IR drainage. Receiver operating characteristic (ROC) analysis demonstrated that a CCI greater than 5.5 effectively excluded patients from cholecystectomy. No significant differences were observed in mortality, LOS, or reintervention rates between treatment groups.
conclusionComorbidity burden, age, and CT morphology are key determinants of management in Type II GBP. While surgery remains the definitive treatment, individualized nonoperative strategies can achieve comparable short- and intermediate-term outcomes in high-risk patients. Larger multicenter studies are required to establish evidence-based guidelines.
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