Evidence map›Paper›PMID 41322779›Full record

ArticleCureus2025

A Case Report and Literature Review: When Should We Treat the Seminal Vesicles in Prostate Cancer?

Rohail Syed, Nitin Vaishampayan, Ramesh Boggula, Michael Joiner, Dongping Shi, Steven R Miller

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rohail SyedDepartment of Oncology, Wayne State University School of Medicine, Detroit, USA.
Nitin VaishampayanDepartment of Oncology, Wayne State University School of Medicine, Detroit, USA.
Ramesh BoggulaDepartment of Oncology, Wayne State University School of Medicine, Detroit, USA.
Michael JoinerDepartment of Oncology, Wayne State University School of Medicine, Detroit, USA.
Dongping ShiDepartment of Oncology, Wayne State University School of Medicine, Detroit, USA.
Steven R MillerDepartment of Oncology, Wayne State University School of Medicine, Detroit, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The most common cancer in men is prostate cancer. Treatment options for prostate cancer consist of radiation therapy, active surveillance, chemotherapy, and surgical intervention. In this case, radiation therapy was used, but it can lead to adverse effects ranging from fatigue, impacted sexual function, genitourinary side effects such as dysuria or nocturia, and gastrointestinal side effects such as nausea, abdominal pain, or diarrhea. Minimizing the treatment only to areas with PET-positive disease and those with a significant risk of microscopic involvement, therefore reducing radiation exposure, can help mitigate side effects and help maintain the patient's quality of life. Here, we examine a man with prostatic adenocarcinoma. A prostate-specific membrane antigen (PSMA)-PET scan was used to determine if the seminal vesicles demonstrated any evidence of disease and if treatment of the area was necessary. A PSMA-PET scan showed invasion of the seminal vesicles; thus, the seminal vesicles were included as a target for radiation therapy. The patient tolerated the treatment with minimal side effects. This case reviews the indications for treating the whole seminal vesicle.

Indexed as

conformal radiation therapyga-68 psma (gallium-68 prostate-specific membrane antigen)pelvic mriprostate cancerradiation therapyseminal vesicle invasion

Identifiers

PMID41322779
PMCPMC12662156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.