Evidence map›Paper›PMID 41322773›Full record

ArticleCureus2025

Unusual Presentation of Giant Cell Arteritis With Localised Temporal Artery Aneurysm.

Syed A Ahmad, Niazi Khairi, Meeran Hussain, Mark Lloyd

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Syed A AhmadGeneral Medicine, Frimley Park Hospital, Camberley, GBR.
Niazi KhairiGeneral Medicine, Frimley Park Hospital, Camberley, GBR.
Meeran HussainGeneral Medicine, Frimley Park Hospital, Camberley, GBR.
Mark LloydRheumatology, Frimley Health NHS Foundation Trust, Camberley, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giant cell arteritis (GCA) is a granulomatous vasculitis of medium and large-sized arteries occurring in older adults. Skip lesions are well described, but to our knowledge, localised aneurysm formation in the context of normocalcaemic, non-progressive GCA has not been reported. We report a case of a 74-year-old male who presented with painless left-sided temporal artery swelling, with an aneurysm and halo sign on ultrasound Doppler (US Doppler). Inflammatory markers were normal. Biopsy of the affected segment confirmed granulomatous inflammation with giant cells. Without treatment, he remained well with subsequent normal inflammatory markers and the US Doppler and positron emission tomography (PET)-CT scan showing no progression of the disease.  This case illustrates the wide spectrum of giant cell arteritis, with the inflammation here being restricted to a focal segment of the superficial temporal artery with normal inflammatory markers and no apparent progression or similar isolated pockets in other areas. The temporal artery aneurysm is also a complication that has not been seen before in the context of GCA. This highlights the importance of considering a diagnosis of GCA, even in the absence of a classical presentation and laboratory findings, based on a potential complication that can help uncover the underlying issue.

Indexed as

colored flow doppler ultrasoundfdg pet/ct scangiant cell arteritis (gca)temporal aortic aneurysmtemporal artertitisvasculitis

Identifiers

PMID41322773
PMCPMC12659966

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.