ArticleCureus2025
Cefepime-Induced Neurotoxicity in an Elderly Patient: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cefepime, a fourth-generation cephalosporin, may cause neurotoxicity, especially in patients with renal impairment. We report an 81-year-old man with chronic kidney disease (CKD) treated with intravenous cefepime for pneumonia. After five days, he developed acute confusion and reduced consciousness. Laboratory results showed no metabolic abnormalities and no microbial growth in blood cultures, and chest X-ray images improved. Cefepime-induced neurotoxicity (CIN) was suspected; the drug was discontinued and replaced with piperacillin-tazobactam. Neurological status recovered fully within 48 hours. This case underscores the need to recognize cefepime neurotoxicity in elderly patients with renal dysfunction, ensuring timely intervention through dose adjustment or discontinuation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.