ArticleInternational journal of dentistry2025
Oral Microbial and Systemic Lipid Profiles in Patients With Asymptomatic Retained Partially Erupted Third Molars: A Preliminary Cross-Sectional Study.
Article in International journal of dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Partially erupted (PE) third molars are frequently retained in the oral cavity and may contribute to localized inflammation. Chronic subclinical inflammation at these sites has been suggested to influence systemic markers such as lipid profiles, potentially increasing cardiovascular risk. Additionally, microbial colonization, particularly by bacteria and Objective: To investigate the lipid panel parameters and oral microbial burden in individuals with PE third molars compared to those with fully erupted (FE) third molars and to assess potential associations with systemic inflammation. Methods: A cross-sectional study was conducted on 64 participants aged 20-35 years, divided into two groups: group 1 with PE third molars and group 2 with FE third molars. Fasting lipid profiles were measured using the CardioChek PA Analyzer. Gingival crevicular fluid (GCF) samples were collected from under the operculum in group 1 and from the gingival sulcus in group 2. Quantitative PCR (qPCR) was used to assess Results: A higher prevalence of elevated total cholesterol (TC) was observed in group 1 (15.63%) compared to group 2, with an odds ratio (OR) of 7.215 (95% CI: 0.992-52.5; Conclusion: PE third molars may be linked to elevated cholesterol levels and increased microbial colonization, particularly by
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